Results 11 to 20 of about 42,626 (296)

Polygenic risk score predicts pathologically confirmed cerebral amyloid angiopathy. [PDF]

open access: yesAlzheimers Dement
Abstract INTRODUCTION Cerebral amyloid angiopathy (CAA) and Alzheimer's disease (AD) both involve amyloid beta (Aβ) accumulation in vessels and brain parenchyma, respectively. As Aβ‐targeting therapies emerge, CAA draws attention due to its link with amyloid‐related imaging abnormalities (ARIA), underscoring the need for biomarkers beyond magnetic ...
Pyun JM   +4 more
europepmc   +2 more sources

Actin-Binding Proteins in Cardiac Hypertrophy

open access: yesCells, 2022
The heart reacts to a large number of pathological stimuli through cardiac hypertrophy, which finally can lead to heart failure. However, the molecular mechanisms of cardiac hypertrophy remain elusive.
Congbin Pan   +3 more
doaj   +1 more source

Trafficking and effect of released DNA on cGAS-STING signaling pathway and cardiovascular disease

open access: yesFrontiers in Immunology, 2023
Evidence from clinical research and animal studies indicates that inflammation is an important factor in the occurrence and development of cardiovascular disease (CVD).
Zimo Zhou   +15 more
doaj   +1 more source

Cerebral Proliferative Angiopathy [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2009
A 31-year-old male presented with transient numbness of the right hand, progressing to involve the forearm. The symptoms lasted for around 30 minutes without any associated weakness or positive motor phenomena. An evaluation in the emergency room revealed no focal deficits.Acomputer tomogram (CT) scan performed in the emergency room suggested a few ...
Muneer, Eesa   +2 more
openaire   +2 more sources

Cerebral amyloid angiopathy [PDF]

open access: yesBMJ Case Reports, 2014
A 72-year-old man presented with headache, vomiting and diminution of vision. There was no history of smoking, diabetes mellitus, hypertension or use of aspirin or recreational drugs. The general physical examination, pulse, blood pressure, chest and cardiovascular examination were normal.
Navneet, Sharma, Sameer, Vyas
openaire   +2 more sources

FOXM1: Functional Roles of FOXM1 in Non-Malignant Diseases

open access: yesBiomolecules, 2023
Forkhead box (FOX) proteins are a wing-like helix family of transcription factors in the DNA-binding region. By mediating the activation and inhibition of transcription and interactions with all kinds of transcriptional co-regulators (MuvB complexes ...
Zhenwang Zhang   +4 more
doaj   +1 more source

Trelagliptin relieved cognitive impairment of diabetes mellitus rats: Involvement of PI3K/Akt/GSK-3β and inflammation pathway

open access: yesExperimental Gerontology, 2023
Cognitive impairment frequently coexists with diabetes. Trelagliptin is a once-weekly taking selective dipeptidyl peptidase-4 (DPP-4) inhibitor and a long-term effective hypoglycemic medicine; nonetheless, its effects for the treatment of diabetes ...
Min Lei   +9 more
doaj   +1 more source

White matter hyper-intensity patters in patients with amyloid angiopathy and cerebellum involvement [PDF]

open access: yesThe Moldovan Medical Journal, 2020
Background: Pathological changes in the cerebral white matter can be determined both in small vessel disease and in cerebral amyloid angiopathy. The pattern of involvement may be different depending on the etiology and severity of the process. Objective
Pavel Gavriliuc   +3 more
doaj   +1 more source

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial [PDF]

open access: yes, 2019
Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy.
Abano, Nenette   +966 more
core   +5 more sources

Hemorheological Failure in the Pathology of Cardio-vascular Complications in Patients with Diabetic Foot Syndrome [PDF]

open access: yes, 2016
The literature that includes the study of cardiovascular complications in patients with diabetic foot syndrome was analyzed. The topicality of this problem is caused by the steady growth of diabetes mellitus morbidity among people.
Кorobko, Е. (Еlina)
core   +2 more sources

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