Results 21 to 30 of about 55,141 (338)

Iatrogenic cerebral amyloid angiopathy: an emerging clinical phenomenon

Journal of Neurology Neurosurgery & Psychiatry, 2022
In the last 6 years, following the first pathological description of presumed amyloid-beta (Aβ) transmission in humans (in 2015) and subsequent experimental confirmation (in 2018), clinical cases of iatrogenic cerebral amyloid angiopathy (CAA)—attributed
G. Banerjee, K. Samra, M. Adams, Z. Jaunmuktane, A. Parry-Jones, J. Grieve, A. Toma, S. Farmer, R. Sylvester, H. Houlden, P. Rudge, S. Mead, S. Brandner, J. Schott, J. Collinge, D. Werring   +15 more
semanticscholar   +1 more source

Rising of intracellular NAD+ level and oppositely directed changes in CD38 expression in hippocampal cells in experimental Alzheimer’s disease

Сибирский научный медицинский журнал, 2021
The aim of the study was to assess the level of NAD+ in the brain of mice treated with beta-amyloid (Aβ), as well as to determine the activity of ADP-ribosyl cyclase/CD38 and the number of CD38-immunopositive neurons, astrocytes and endothelial cells ...
A. A. Semenova, Ya. V. Gorina, E. D. Khilazheva, E. V. Kharitonova, A. B. Salmina   +4 more
doaj   +1 more source

Actin-Binding Proteins in Cardiac Hypertrophy

Cells, 2022
The heart reacts to a large number of pathological stimuli through cardiac hypertrophy, which finally can lead to heart failure. However, the molecular mechanisms of cardiac hypertrophy remain elusive.
Congbin Pan, Siqi Wang, Chao Liu, Zhanhong Ren   +3 more
doaj   +1 more source

Spontaneous ARIA-like Events in Cerebral Amyloid Angiopathy–Related Inflammation

Neurology, 2021
Background and Objectives The goal of this work was to investigate the natural history and outcomes after treatment for spontaneous amyloid-related imaging abnormalities (ARIA)-like in cerebral amyloid angiopathy–related inflammation (CAA-ri).
L. Antolini, J. DiFrancesco, M. Zedde, G. Basso, A. Arighi, Atsushi Shima, A. Cagnin, M. Caulo, Roxana O. Carare, A. Charidimou, M. Cirillo, V. Di Lazzaro, C. Ferrarese, A. Giossi, D. Inzitari, M. Marcon, R. Marconi, M. Ihara, R. Nitrini, B. Orlandi, A. Padovani, R. Pascarella, F. Perini, G. Perini, M. Sessa, E. Scarpini, F. Tagliavini, R. Valenti, J. Vázquez-Costa, A. Villarejo-Galende, Yuta Hagiwara, N. Ziliotto, F. Piazza   +32 more
semanticscholar   +1 more source

Tirzepatide ameliorates spatial learning and memory impairment through modulation of aberrant insulin resistance and inflammation response in diabetic rats

Frontiers in Pharmacology, 2023
Background: One of the typical symptoms of diabetes mellitus patients was memory impairment, which was followed by gradual cognitive deterioration and for which there is no efficient treatment.
Xiying Guo, Min Lei, Jiangyan Zhao, Min Wu, Zhanhong Ren, Xiaosong Yang, Changhan Ouyang, Xiufen Liu, Chao Liu, Qingjie Chen   +9 more
doaj   +1 more source

Cerebrospinal fluid biomarkers for cerebral amyloid angiopathy

Brain Communications, 2023
Integrating cerebrospinal fluid-biomarkers into diagnostic workup of patients with sporadic cerebral amyloid angiopathy may support early and correct identification.
J. Sembill, Christoph Lusse, M. Linnerbauer, M. Sprügel, Anne Mrochen, Michael Knott, T. Engelhorn, M. Schmidt, A. Doerfler, T. Oberstein, J. Maler, J. Kornhuber, P. Lewczuk, Veit Rothhammer, S. Schwab, J. Kuramatsu   +15 more
semanticscholar   +1 more source

Trafficking and effect of released DNA on cGAS-STING signaling pathway and cardiovascular disease

Frontiers in Immunology, 2023
Evidence from clinical research and animal studies indicates that inflammation is an important factor in the occurrence and development of cardiovascular disease (CVD).
Zimo Zhou, Zimo Zhou, Changhan Ou-yang, Changhan Ou-yang, Qingjie Chen, Qingjie Chen, Zhanhong Ren, Zhanhong Ren, Xiying Guo, Xiying Guo, Min Lei, Min Lei, Chao Liu, Chao Liu, Xiaosong Yang, Xiaosong Yang   +15 more
doaj   +1 more source

Cerebral Proliferative Angiopathy [PDF]

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2009
A 31-year-old male presented with transient numbness of the right hand, progressing to involve the forearm. The symptoms lasted for around 30 minutes without any associated weakness or positive motor phenomena. An evaluation in the emergency room revealed no focal deficits.Acomputer tomogram (CT) scan performed in the emergency room suggested a few ...
Muneer, Eesa, Pranshu, Sharma, Mayank, Goyal   +2 more
openaire   +2 more sources

Cerebral amyloid angiopathy [PDF]

BMJ Case Reports, 2014
A 72-year-old man presented with headache, vomiting and diminution of vision. There was no history of smoking, diabetes mellitus, hypertension or use of aspirin or recreational drugs. The general physical examination, pulse, blood pressure, chest and cardiovascular examination were normal.
Navneet, Sharma, Sameer, Vyas
openaire   +2 more sources

Increased Neuromedin B is Associated with a Favorable Prognosis in Glioblastoma

Frontiers in Bioscience-Landmark, 2023
Background: Neuromedin B (NMB) is a neuropeptide that plays a key role in many physiological processes and is involved in the pathology of various diseases. Increased levels of NMB have been reported in solid tumors.
Suqin Li, Shihuan Li, Qingjie Li, Fei Liu, Wenli Liao, Liangzhu Yu, Changhan Ouyang, Hongli Xia, Chao Liu, Mincai Li   +9 more
doaj   +1 more source