Results 101 to 110 of about 7,590,894 (205)
, 2014 Item does not contain fulltextThe angiopoietin-like protein 4 (angptl4, also known as peroxisome proliferator-activated receptor [PPAR]gamma-induced angiopoietin-related protein) is a multifunctional protein associated with acute-phase response.
Marcondes, A.M. +9 more
core +1 more source
Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source
, 2016 Angiopoietin-1 levels and other baseline parameters as predictors of overall mortality/transplant in patients with different PH subtypes.
Manuel Jonas Richter (2586910) +7 more
core +1 more source
British Journal of Pharmacology, EarlyView.Long non‐coding RNAs (lncRNAs), a broad class of non‐protein‐coding RNAs, are characterized as new regulators of gene expression at the epigenetic, transcriptional, and post‐transcriptional level. Thus, lncRNAs are involved in the regulation of physiological processes and the development of human diseases and cancer by modulating proinflammatory ...
Charlie Leboff +3 more
wiley +1 more source
Cell Proliferation, EarlyView.During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu +5 more
wiley +1 more source
, 2011 Angiopoietin-like protein (Angptl) 1, a member of the angiopoietin- related protein family, modulates angiogenesis but little else is known of its physiological role.
LAI, DAR-MING;LI, HUNG;LEE, CHIN-CHENG;TZENG, YI-SHIUAN;HSU, WEN-MING;HSIEH, FON-JOU;CHENG, JUEI-TANG;TU, YONG-KWANG +1 more
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Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest +3 more
wiley +1 more source
EMBO Molecular Medicine, 2012 Homing of colorectal cancer (CRC) cells to the liver is a non‐random process driven by a crosstalk between tumour cells and components of the host tissue. Here we report the isolation of a liver metastasis‐specific peptide ligand (CGIYRLRSC) that binds a
Serena Marchiò +19 more
doaj +1 more source
, 1999 During development of the vertebrate vascular system essential signals are transduced via protein-tyrosine phosphorylation. Null-mutations of receptor-tyrosine kinase (RTK) genes expressed in endothelial cells (ECs) display early lethal vascular ...
Deutsch, U, Fachinger, G, Risau, W
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Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims To further characterise the effects of retatrutide on cardiometabolic risk, lipoprotein and inflammatory biomarkers were assessed post hoc in phase 2 trials of adults with obesity/overweight with or without type 2 diabetes (T2D). Materials and Methods Data were analysed from two randomised, double‐blind, placebo‐controlled phase 2 trials.
Giacomo Ruotolo +13 more
wiley +1 more source