Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue [PDF]
Molecular Metabolism, 2022 Objective: Brown adipose tissue (BAT) burns fatty acids (FAs) to produce heat, and shows diurnal oscillation in glucose and triglyceride (TG)-derived FA-uptake, peaking around wakening. Here we aimed to gain insight in the diurnal regulation of metabolic
Robin van Eenige +16 more
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Inhaled Angiopoietin‐Like 4 Antisense Oligonucleotide Therapy for Lung Injury and Fibrosis [PDF]
Advanced SciencePulmonary infections and fibrosis remain difficult to treat because current interventions target isolated pathways rather than the coupled axes of inflammation, barrier integrity, and tissue remodeling.
Haiyang Fan +21 more
doaj +2 more sources
Suppression of angiopoietin-like 4 reprograms endothelial cell metabolism and inhibits angiogenesis [PDF]
Nature Communications, 2023 Angiopoietin-like 4 (ANGPTL4) is known to regulate various cellular and systemic functions. However, its cell-specific role in endothelial cells (ECs) function and metabolic homeostasis remains to be elucidated.
Balkrishna Chaube +11 more
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Angiopoietin‐like 4 is a potential biomarker for diabetic kidney disease in type 2 diabetes patients [PDF]
Journal of Diabetes InvestigationAims/Introduction The association between serum angiopoietin‐like 4 (ANGPTL4) levels and the severity of diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus remains unclear.
Yan Wang +12 more
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Relationship between serum angiopoietin-like 4 levels and recurrence of atrial fibrillation [PDF]
Journal of International Medical Research, 2021 Objective To investigate the association between serum angiopoietin-like 4 (ANGPTL4) levels and recurrence of atrial fibrillation (AF) after catheter ablation.
Zhongping Ning +4 more
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Angiopoietin-like-4 and minimal change disease. [PDF]
PLoS ONE, 2017 BACKGROUND:Minimal Change Disease (MCD) is the most common type of nephrotic syndrome in children. Angiopoietin-like-4 (Angplt4) has been proposed as mediator of proteinuria in MCD. The aim of this study was to evaluate the role of Angptl4 as a biomarker
Gabriel Cara-Fuentes +6 more
doaj +2 more sources
Elevated Plasma Angiopoietin-like 4 Protein Levels in Adult Patients with Dengue [PDF]
VirusesDengue virus infection can cause severe complications due to vascular leakage. Angiopoietin-like protein 4 (ANGPTL4) regulates vascular permeability, but its role in dengue pathogenesis is unclear.
Win Khaing +9 more
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Angiopoietin-Like 4 (ANGPTL4) in Patients with Psoriasis, Lichen Planus and Vitiligo—A Pilot Study from the Bialystok+ Polish Longitudinal University Study [PDF]
Metabolites, 2022 Psoriasis, vitiligo and lichen planus (LP) are autoimmune skin diseases associated with metabolic syndrome. Angiopoietin-like 4 (ANGPTL4) is a member of angiopoietin-like proteins, which play an important role in lipid metabolism, and its serum ...
Julia Nowowiejska +8 more
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Helicobacter pylori-Induced Angiopoietin-Like 4 Promotes Gastric Bacterial Colonization and Gastritis [PDF]
ResearchHelicobacter pylori infection is characterized as progressive processes of bacterial persistence and chronic gastritis with features of infiltration of mononuclear cells more than granulocytes in gastric mucosa.
Rui Xie +23 more
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On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity
Journal of Lipid Research, 2019 Angiopoietin-like (ANGPTL) 8 is a secreted inhibitor of LPL, a key enzyme in plasma triglyceride metabolism. It was previously reported that ANGPTL8 requires another member of the ANGPTL family, ANGPTL3, to act on LPL.
Oleg Kovrov +4 more
doaj +3 more sources