Results 1 to 10 of about 16,714,816 (218)

Targeted Knockdown of Hepatic Δ-5 Fatty Acid Desaturase FADS1 Aggravates Atherosclerosis in ApoE-/- Mice

Frontiers in Bioscience-Landmark
Background: The endogenous metabolism of polyunsaturated fatty acids is regulated by the fatty acid desaturase (FADS) gene cluster and is strongly associated with diseases such as atherosclerosis, dyslipidemia, and type 2 diabetes.
Qiulei Liu, Peng Wang, Zhao Yang, Yue Dai, Sheng Wang   +4 more
doaj   +1 more source

Angiopoietin-like 4 (ANGPTL4) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Identification and expression analysis of bovine ANGPTL gene family

Current Zoology, 2010
Encoded by seven genes, angiopoietin-like (ANGPTL) family members structurally similar to the angiogenic regulating factor angiopoietin are known to possess biological activities in angiogenesis and metabolism.
Zhengbing GUAN,Guolin CAI, Junyong SUN, Jian LU
doaj  

Angiopoietin-like 4 in glucocorticoid induced insulin resistance

Oncotarget, 2017
Lee, Rebecca A, Wang, Jen-Chywan
openaire   +4 more sources

Angiopoietin-like 4 (ANGPTL4); integrin αVβ5 [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Angiopoietin-like 4 promotes terminal chondrogenic differentiation [PDF]

Osteoarthritis and Cartilage, 2012
Mathieu, M., Chuchana, P., Iampietro, M., Noël, D., Jorgensen, C.   +4 more
openaire   +1 more source

Angiopoietin-like-4 is a potential angiogenic mediator in arthritis

Clinical Immunology, 2005
Our previous studies of gene expression profiling during collagen-induced arthritis (CIA) indicated that the putative angiogenic factor Angptl4 was one of the most highly expressed mRNAs early in disease. To investigate the potential involvement of Angptl4 in CIA pathogenesis, Angptl4 protein levels were assessed at early stages of disease and its ...
Hermann, L.M., Pinkerton, M., Jennings, K., Yang, L., Grom, A., Sowders, D., Kersten, A.H., Witte, D.P., Hirsch, R., Thornton, S.   +9 more
openaire   +3 more sources

Circadian Angiopoietin-Like-4 as a Novel Therapy in Cardiovascular Disease

Trends in Molecular Medicine, 2021
Angiopoietin-like 4 (ANGPTL4) is critical for regulating plasma lipids, and thus an attractive therapeutic target for cardiovascular diseases. Unfortunately, targeting ANGPTL4 results in a proinflammatory and ultimately lethal phenotype in animals. The serendipitous discovery of cardiac ANGPTL4 as a circadian protein reveals novel mechanistic insight ...
Sydney, Shuff, Yoshimasa, Oyama, Lori, Walker, Tobias, Eckle   +3 more
openaire   +2 more sources

Response of Angiopoietin-like Proteins 3 and 4 to Hemodialysis

The International Journal of Artificial Organs, 2014
Background/Aim Patients on chronic hemodialysis (cHD) have decreased activity of lipoprotein lipase (LPL). Angiopoietin-like proteins (ANGPTL) 3 and 4 have been shown to inactivate LPL. The aim of this study was to investigate the levels of the ANGPTLs in plasma of cHD-patients and to evaluate if cHD may alter ...
Dana, Mahmood, Elena, Makoveichuk, Solveig, Nilsson, Gunilla, Olivecrona, Bernd, Stegmayr   +4 more
openaire   +2 more sources

Genetics and regulation of angiopoietin-like proteins 3 and 4

Current Opinion in Lipidology, 2006
Lipoprotein lipase activity in a given tissue is the rate limiting step for the uptake of triglyceride-derived fatty acids. Imbalances in the partitioning of fatty acids have major metabolic consequences. Given the central role of lipoprotein lipase in energy metabolism, the discovery of new molecules that affect the activity of lipoprotein lipase ...
openaire   +2 more sources