Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. [PDF]
, 2013 We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors.
Di Qin (107446) +20 more
core +2 more sources
Angiopoietin-like 4 governs diurnal lipoprotein lipase activity in brown adipose tissue
Molecular Metabolism, 2022 Objective: Brown adipose tissue (BAT) burns fatty acids (FAs) to produce heat, and shows diurnal oscillation in glucose and triglyceride (TG)-derived FA-uptake, peaking around wakening. Here we aimed to gain insight in the diurnal regulation of metabolic
Robin van Eenige +16 more
doaj +1 more source
Angiopoietin-like protein 4 and cardiovascular function in COPD [PDF]
BMJ Open Respiratory Research, 2016 Introduction The coexistence of chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) is frequent and might be inter-related through inflammation-related processes reflected by specific markers.
B Waschki +9 more
openaire +2 more sources
Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria [PDF]
, 2009 Background Severe and cerebral malaria are associated with endothelial activation. Angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2) are major regulators of endothelial activation and integrity.
Liles W Conrad +21 more
core +1 more source
Increased Level of Angiopoietin Like Proteins 4 and 8 in People With Sleep Apnea
Frontiers in Endocrinology, 2018 Objective: Obstructive sleep apnea (OSA) is a sleep disorder caused by the complete or partial obstruction of the upper airways. The worldwide prevalence of OSA is increasing due to its close association with obesity epidemic and multiple health ...
Abdulmohsen Al-Terki +9 more
doaj +1 more source
On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity
Journal of Lipid Research, 2019 Angiopoietin-like (ANGPTL) 8 is a secreted inhibitor of LPL, a key enzyme in plasma triglyceride metabolism. It was previously reported that ANGPTL8 requires another member of the ANGPTL family, ANGPTL3, to act on LPL.
Oleg Kovrov +4 more
doaj +1 more source
Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children. [PDF]
, 2009 BACKGROUND: Limited tools exist to identify which individuals infected with Plasmodium falciparum are at risk of developing serious complications such as cerebral malaria (CM). The objective of this study was to assess serum biomarkers that differentiate
Hawkes, Michael +38 more
core +1 more source
mRNA Expression of Ovine Angiopoietin-like Protein 4 Gene in Adipose Tissues [PDF]
Asian-Australasian Journal of Animal Sciences, 2016 Angiopoietin-like protein 4 (ANGPTL4) is involved in a variety of functions, including lipoprotein metabolism and angiogenesis. To reveal the role of ANGPTL4 in fat metabolism of sheep, ovine ANGPTL4 mRNA expression was analyzed in seven adipose tissues ...
Jing Zhang +6 more
doaj +1 more source
Suppression of angiopoietin-like 4 reprograms endothelial cell metabolism and inhibits angiogenesis
Nature Communications, 2023 Angiopoietin-like 4 (ANGPTL4) is known to regulate various cellular and systemic functions. However, its cell-specific role in endothelial cells (ECs) function and metabolic homeostasis remains to be elucidated.
Balkrishna Chaube +11 more
doaj +1 more source
The role of angiopoietin-like 4 in inflammation [PDF]
, 2020 Inflammation is a homeostatically fundamental feature of the host defence surveillance system made up of an army of sentinel cells that guard against foreign intrusion.
openaire +3 more sources