Results 21 to 30 of about 16,714,816 (218)

Multiple Roles of Angiopoietin-Like 4 in Osteolytic Disease [PDF]

Frontiers in Endocrinology, 2017
Hypoxia and the hypoxia-inducible factor (HIF) transcription factor drive pathological bone loss in conditions including rheumatoid arthritis (RA), osteoarthritis, osteoporosis, primary bone tumours, and bone metastatic cancer. There is therefore considerable interest in determining the function(s) of HIF-induced genes in these pathologies ...
Helen J. Knowles, Knowles, H, Knowles, Helen   +2 more
openaire   +4 more sources

Angiopoietin-like 2 Protein and Hidradenitis Suppurativa: A New Biomarker for Disease Severity [PDF]

Biomedicines, 2023
Hidradenitis suppurativa (HS) is a chronic inflammatory disease whose pathogenesis is not fully understood at present. The role of proinflammatory cytokines, several adipokines, retinol-binding protein 4, angiopoietin-2 and other molecules has been ...
José L. Hernández, J. Gonzalo Ocejo-Vinyals, Mónica Renuncio-García, Elena González-López, Ricardo Blanco, Marcos A. González-López   +5 more
doaj   +2 more sources

Role of angiopoietin-like 4 in tumor growth. [PDF]

, 2019
Cancer is a leading cause of death worldwide. Tumor cells exploit various signaling molecules to promote their growth and metastasis. The angiopoietin-like 4 protein (ANGPTL4) has well-studied roles in metabolism, yet its role in cancer biology remains undefined. Herein, by using human tumor tissue arrays, tumor cell lines and human skin tumor samples,
Zhu, Pengcheng.
openaire   +3 more sources

Angiopoietin‐like protein 4 and clinical outcomes in ischemic stroke patients

Annals of Clinical and Translational Neurology, 2021
Aims Angiopoietin‐like protein 4 (ANGPTL‐4) had been reported to be associated with the risk of ischemic stroke, but its prognostic value remained unclear.
Xiaowei Zheng, Suwen Shen, Aili Wang, Zhengbao Zhu, Yanbo Peng, Hao Peng, Chongke Zhong, Daoxia Guo, Tan Xu, Jing Chen, Zhong Ju, Deqin Geng, Yonghong Zhang, Jiang He   +13 more
doaj   +1 more source

Role of Angiopoietin-like protein 4 (ANGPTL4) as a Predictive marker for Diabetic Nephropathy in type 2 Diabetes [PDF]

Al-Azhar International Medical Journal, 2022
Background: Angiopoietin-like protein 4 (ANGPTL4) is a glycoprotein that regulates LPL activity during fasting and thereby affects triglyceride metabolism.
Amr Rezk, hossam aladl, youssef Ahmed, ahmed abd elhakam   +3 more
doaj   +1 more source

The Prognostic Value of ANGPTL-4 in Acute Coronary Syndrome: A Prospective Cohort Study [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Coronary Artery Disease (CAD) is one of the leading causes of mortality and morbidity worldwide and Acute Coronary Syndrome (ACS) is one of the predominant causes of Cardiovascular Deaths (CVD).
Luxitaa Goenka, Ritwika Sinha Ray, Vengatesh Munnusamy, VE Dhandapani, Melvin George   +4 more
doaj   +1 more source

Angiopoietin-like protein 4 regulates breast muscle lipid metabolism in broilers

Poultry Science, 2021
: The objective of this study was to determine the effects of angiopoietin-like protein 4 (ANGPTL4) on breast muscle lipid metabolism in broilers. In experiment 1, 36 thirty-five-day-old male Arbor Acres broilers were randomly allocated into 6 treatment ...
Xu Zhao, Huashan Huang, Xiao Ding, Zaibin Yang, Yanru Hou, Hongfang Wang   +5 more
doaj   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

A review of the multifunctionality of angiopoietin-like 4 in eye disease [PDF]

Bioscience Reports, 2018
Angiopoietin-like protein 4 (ANGPTL4) is a multifunctional cytokine regulating vascular permeability, angiogenesis, and inflammation. Dysregulations in these responses contribute to the pathogenesis of ischemic retinopathies such as diabetic retinopathy (DR), age-related macular degeneration (AMD), retinal vein occlusion, and sickle cell retinopathy ...
Yang, Xinyue, Cheng, Yan, Su, Guanfang
openaire   +2 more sources

Angiopoietin-like 4 and ischaemic stroke: a promising start [PDF]

European Heart Journal, 2013
This editorial refers to ‘Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke,[†][1]’ by C. Bouleti et al. , on page 3657 Stroke is a global cause of morbidity and mortality, ranking fourth among all causes of death.1 Although considerable progress has been made in developing effective tools for ...
Spescha Remo D, Sessa Maria, Camici Giovanni G.   +2 more
openaire   +3 more sources