Results 261 to 270 of about 470,839 (363)

Angiotensin-converting enzyme in innate and adaptive immunity

open access: yesNature Reviews Nephrology, 2018
K. Bernstein   +5 more
semanticscholar   +1 more source

Re‐PERFUSE: Phase 1b study of AZD3427, a novel relaxin receptor agonist, on renal perfusion in HFrEF patients

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Renal impairment frequently coexists with heart failure (HF) and is associated with increased risk of poor clinical outcomes. This highlights the urgent need for therapies targeting both cardiac and renal dysfunction. AZD3427, a long‐acting recombinant fusion protein and relaxin analogue that selectively activates the relaxin family ...
Marcin Ufnal   +9 more
wiley   +1 more source

Geographic region variation in patient characteristics, clinical outcomes and treatment of HFrEF in the VICTORIA trial

open access: yesESC Heart Failure, EarlyView.
Central Illustration caption: This analysis of vericiguat's treatment effect revealed no inter‐geographic region heterogeneity for the primary composite endpoint (time to HF‐related hospitalization or cardiovascular (CV) death or its components) (Left Panel).
Cynthia M. Westerhout   +9 more
wiley   +1 more source

Percutaneous endocardial alginate–hydrogel injection in the treatment of heart failure: First‐in‐human study

open access: yesESC Heart Failure, EarlyView.
Using EndoWings™ and XDROP™, we developed a percutaneous minimally invasive technique for sequential circumferential alginate hydrogel injection into LV free mid‐wall. This human study assessed its safety/feasibility in HFrEF patients, with personalised biomechanical models.
Bo Wang   +13 more
wiley   +1 more source

Nurse‐coordinated multidisciplinary comprehensive heart failure management programme: A propensity‐matched trial

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Despite therapeutic advancements, the prognosis of heart failure (HF) remains poor, with high rates of mortality and readmission, particularly following a HF exacerbation. This study aimed to evaluate the effects of a nurse‐coordinated multidisciplinary comprehensive HF management programme on HF patients.
Cecilia Miu‐Ching Chan   +13 more
wiley   +1 more source

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