Emerging pharmacological treatments to prevent abdominal aortic aneurysm growth and rupture [PDF]
Abdominal aortic aneurysm (AAA) is a local expansion of the abdominal aorta wall caused by a complex multifactorial maladaptive vascular remodeling. Despite recent advances in the management of cardiovascular diseases, there currently is no established ...
Fraga-Silva, Rodrigo +2 more
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Chao Zhang, Jun Zhong, Wei-Xiang Chen, Xu-Yang Zhang, Yu-Hong Li, Teng-Yuan Zhou, Yong-Jie Zou, Chuan Lan, Lan Li, Zhao-Pan Lai, Hua Feng, Rong Hu Department of Neurosurgery and Key Laboratory of Neurotrauma, Southwest Hospital, Third Military Medical ...
Zhang C +11 more
doaj
Tissue Angiotensin II Generating System by Angiotensin-Converting Enzyme and Chymase
.: It had been believed that angiotensin II (Ang II) was produced by the renin-angiotensin system (RAS), which was established in the 1950’s. After a while, people realized that the multiple functions of Ang II could not be explained by the conventional ...
Mizuo Miyazaki, Shinji Takai
doaj +1 more source
Onset of experimental severe cardiac fibrosis is mediated by overexpression of angiotensin-converting enzyme 2 [PDF]
Angiotensin-converting enzyme (ACE) 2 is a recently identified homologue of ACE. There is great interest in the therapeutic benefit for ACE2 overexpression in the heart.
Allen, James M. +12 more
core +1 more source
Postoperative angioedema induced by angiotensin-converting enzyme inhibitor: case report [PDF]
Background and objectives: Angioedema is a potentially fatal condition that may occur at any time in the perioperative period. It may result from histamine release, hypersensitivity reaction to drugs, or be triggered by bradykinin, in non-allergic ...
Flora Margarida Barra Bisinotto +4 more
doaj +5 more sources
BackgroundAlbuminuria is a marker of inflammation and an independent predictor of cardiovascular morbidity and mortality. The current study evaluated whether eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplementation attenuates ...
Tarec K. Elajami +5 more
doaj +1 more source
The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae [PDF]
Background Members of the M2 family of peptidases, related to mammalian angiotensin converting enzyme (ACE), play important roles in regulating a number of physiological processes.
Burnham, S. +4 more
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Icatibant in the Treatment of Angiotensin-Converting Enzyme Inhibitor-Induced Angioedema
We describe the case of a 75-year-old woman who presented with massive tongue and lip swelling secondary to angiotensin-converting enzyme inhibitor-induced angioedema. An awake fibre-optic intubation was performed because of impending airway obstruction.
Neil H. Crooks +3 more
doaj +1 more source
Isolated Visceral Angioedema Induced by Angiotensin-Converting Enzyme Inhibitor
Visceral angioedema is a rare complication of therapy with angiotensin-converting enzyme (ACE) inhibitors. Clinical presentation includes nausea, vomiting, abdominal pain and diarrhea.
Ana Maria Oliveira +4 more
doaj +1 more source
Individualized Angiotensin‐Converting Enzyme (ACE)‐Inhibitor Therapy in Stable Coronary Artery Disease Based on Clinical and Pharmacogenetic Determinants: The PERindopril GENEtic (PERGENE) Risk Model [PDF]
Patients with stable coronary artery disease (CAD) constitute a heterogeneous group in which the treatment benefits by angiotensin-converting enzyme (ACE)-inhibitor therapy vary between individuals.
Akkerhuis, KM +14 more
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