Effective therapy of hypertension from the standpoint of patient-centered medicine
The article presents current data on the choice of antihypertensives from the standpoint of patient-centered medicine. The advantages of combined initial therapy includes high medical adherence, achievement of target blood pressure, and organ protection.
V. I. Podzolkov +6 more
doaj +1 more source
Angiotensin Converting Enzyme Gene Insertion/Deletion Polymorphism in Migraine Patients
OBJECTIVE: The beneficial effects of angiotensin converting enzyme inhibitor drugs on migraine attack frequency have been shown. We aimed to study the relationship between the angiotensin converting enzyme gene and migraine pathophysiology.
Belgin Alaşehirli +8 more
doaj
Captopril-Associated Cough Is Not due to Increased Airway Responsiveness
BACKGROUND: Angiotensin-converting enzyme (ACE) inhibitors commonly cause cough. There is controversy as to whether preexisting airway hyperresponsivencss predisposes patients to ACE inhibitor-induced cough and whether ACE inhibitor therapy can cause ...
SP Blackie +4 more
doaj +1 more source
Differential renal effects of candesartan at high-and ultra-high doses in diabetic mice: potential role of ACE2/AT2R/Mas [PDF]
High doses of Ang II receptor (AT1R) blockers (ARBs) are renoprotective in diabetes. Underlying mechanisms remain unclear. We evaluated whether high/ultra-high doses of candesartan (ARB) up-regulate angiotensin-converting enzyme 2 (ACE2)/Ang II type 2 ...
Antunes, Tayze +10 more
core +1 more source
Effectiveness of C1-INH therapy in angiotensin converting enzyme inhibitor induced angioedema
Introduction Angiotensin Converting Enzyme Inhibitors (ACEI) are a common cause of Emergency Room presentation for angioedema. Although no treatment guidelines exist, C1 esterase inhibitor concentrate (C1-INH) is used on an off label basis for management
Uliana Kovaltchouk +3 more
doaj +1 more source
Microalbuminaria in hypertension: a review
Microalbuminuria appears early in the natural history of kidney disease. Hypertension accelerates the progressive increase in albuminuria and decline in glomerular filtration rate, albuminuria is the most important risk for progressive kidney injury ...
Mahesh Bhattarai, Buna Bhandari
doaj +1 more source
Worsening renal function and outcome in heart failure patients with reduced and preserved ejection fraction and the impact of angiotensin receptor blocker treatment: data from the CHARM-study programme [PDF]
Aims We investigated the association between worsening renal function (WRF) that occurs during renin–angiotensin–aldosterone system inhibition initation and outcome in heart failure (HF) patients with preserved ejection fraction (HFPEF) and compared ...
Brenner +21 more
core +1 more source
COVID-19 and chronological aging : senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection? [PDF]
COVID-19, also known as SARS-CoV-2, is a new emerging zoonotic corona virus of the SARS (Severe Acute Respiratory Syndrome) and the MERS (Middle East Respiratory Syndrome) family.
Auwerx +30 more
core +2 more sources
Aliskiren, enalapril, or aliskiren and enalapril in heart failure [PDF]
BACKGROUND Among patients with chronic heart failure, angiotensin-converting–enzyme (ACE) inhibitors reduce mortality and hospitalization, but the role of a renin inhibitor in such patients is unknown.
] +15 more
core +5 more sources
Pharmacist intervention in primary care to improve outcomes in patients with left ventricular systolic dysfunction [PDF]
<b>Background</b> Meta-analysis of small trials suggests that pharmacist-led collaborative review and revision of medical treatment may improve outcomes in heart failure.<p></p> <b>Methods and results</b> We studied
Forsyth, P. +7 more
core +1 more source

