Results 71 to 80 of about 106,090 (294)

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali, Stephan van Erp, Cornelis Kramers, Cornelis J. Tack, Bastiaan E. de Galan   +4 more
wiley   +1 more source

Characterizing Alzheimer’s Disease and Related Dementia in a Hypertension Population Within the State of Florida Using Electronic Health Record–Based Data

Clinical Pharmacology &Therapeutics, EarlyView.
Hypertension is a known modifiable risk factor for Alzheimer’s disease and related dementia (ADRD). However, it is unknown how variance in hypertension control, antihypertensive medications, and social determinants of health, such as social deprivation index (SDI), influence the risk of developing ADRD.
Eissa A. Jafari, Mona Alshahawey, Muhammad A. Zaman, Steven M. Smith, Yan Gong, Glenn E. Smith, Caitrin W. McDonough   +6 more
wiley   +1 more source

Angioedema of the small bowel caused by angiotensin converting enzyme inhibitor

Journal of the Belgian Society of Radiology, 2013
A 69-year-old male with a previous history of atrial fibrillation and hypertension was admitted to the emergency department because of acute onset of abdominal pain, accompanied by distension, nausea and diarrhea.
B S Smet, I De Kock, A I De Backer, K Verstraete   +3 more
doaj   +1 more source

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

Clinical Pharmacology &Therapeutics, EarlyView.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park, Jae‐Hwan Lee, Jin‐Ok Jeong, Diana A. Gorog, Udaya S. Tantry, Byeong‐Keuk Kim, Hyung Joon Joo, Kiyuk Chang, Jin‐Yong Hwang, Young Bin Song, Sung Gyun Ahn, Jung‐Won Suh, Woong Gil Choi, Jung Rae Cho, Jeehoon Kang, Sang Yeub Lee, Hyo‐Soo Kim, Moo Hyun Kim, Do‐Sun Lim, Eun‐Seok Shin, Paul A. Gurbel, Young‐Hoon Jeong, on behalf of the PTRG‐DES Consortium Investigators   +22 more
wiley   +1 more source

Contrasting effects of steroids and angiotensin‐converting‐enzyme inhibitors in a mouse model of dystrophin‐deficient cardiomyopathy [PDF]

, 2009
Ralf Bauer, Volker Straub, A. Blain, Kate Bushby, Guy A. MacGowan   +4 more
openalex   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

Clinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

Renin-Angiotensin System Blockers and Renal Functional Reserve. Is There a Limit of Renoprotection?

Počki, 2015
Renin-angiotensin system (RAS) blockers (angiotensin converting enzyme inhibitors, angiotensin receptor blockers, direct renin inhibitor) have a renoprotective effect in the presence of preserved glomerular filtration rate in patients with chronic kidney
D.D. Ivanov
doaj   +1 more source

Combining angiotensin-receptor blockers with angiotensin-converting-enzyme inhibitors [PDF]

, 2011
Christopher O. Phillips
openalex   +1 more source

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, EarlyView.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Angiotensin‐converting enzyme inhibitors or angiotensin II receptor blockers and prognosis of hypertensive patients hospitalised with COVID‐19 [PDF]

, 2020
Marcello Covino, Giuseppe De Matteis, Maria Livia Burzo, Michele Santoro, Mariella Fuorlo, Luca Sabia, Claudio Sandroni, Antonio Gasbarrini, Francesco Franceschi, Giovanni Gambassi, Gemelli Against COVID‐19 Group   +10 more
openalex   +1 more source