Results 101 to 110 of about 268,538 (298)

Angiotensin-converting enzyme inhibitor fetopathy. [PDF]

open access: yesJournal of the American Society of Nephrology, 1993
Angiotensin-converting enzyme (ACE) inhibitors are widely used for controlling hypertension. Their use in women who are pregnant is not without risk to the fetus. We describe three infants exposed in utero to ACE inhibitors who had adverse outcomes.
Mason Barr   +3 more
openaire   +3 more sources

Effect of short time captopril administration on spatial memory in aging rats [PDF]

open access: yes, 2015
Introduction: The brain renin-angiotensin system (RAS) has been reported having a pathological role in age-related impairment in learning and memory. Therefore, angiotensin converting enzyme inhibitors (ACEi) are expected to have positive ef fects on ...
Bakhshandeh, F., Ganji, F., Sepehri, H.
core  

Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain [PDF]

open access: yes, 2008
Angiotensin-converting enzyme-2 (ACE2) is a regulatory protein of the renin–angiotensin system (RAS) and a receptor for the causative agent of severe-acute respiratory syndrome (SARS), the SARS-coronavirus.
Aichem   +32 more
core   +1 more source

Design of a folding inhibitor of the HIV-1 Protease [PDF]

open access: yesarXiv, 2004
Being HIV-1-PR an essential enzyme in the viral life cycle, its inhibition can control AIDS. Because the folding of single domain proteins, like HIV-1-PR is controlled by local elementary structures (LES, folding units stabilized by strongly interacting, highly conserved amino acids) which have evolved over myriads of generations to recognize and ...
arxiv  

The role of renin-angiotensin system and angiotensin-converting enzyme 2 (ACE2) in the development and course of viral infection COVID-19 in patients with diabetes mellitus

open access: yesСахарный диабет, 2020
The role of renin-angiotensin system (RAS) in general and angiotensin-converting enzyme 2 (ACE2) in particular in the  pathogenesis and course of viral infection caused by SARS-CoV-2 (COVID-19) is of particular interest.
O. K. Vikulova   +3 more
doaj   +1 more source

Angiotensin-converting enzyme inhibitors reduce mortality in hypertension: a meta-analysis of randomized clinical trials of renin–angiotensin–aldosterone system inhibitors involving 158 998 patients

open access: yesEuropean Heart Journal, 2012
Aims Renin–angiotensin–aldosterone system (RAAS) inhibitors are well established for the reduction in cardiovascular morbidity, but their impact on all-cause mortality in hypertensive patients is uncertain.
L. V. van Vark   +6 more
semanticscholar   +1 more source

A folding inhibitor of the HIV-1 Protease [PDF]

open access: yesarXiv, 2005
Being the HIV-1 Protease (HIV-1-PR) an essential enzyme in the viral life cycle, its inhibition can control AIDS. The folding of single domain proteins, like each of the monomers forming the HIV-1-PR homodimer, is controlled by local elementary structures (LES, folding units stabilized by strongly interacting, highly conserved, as a rule hydrophobic ...
arxiv  

The Complexity of Molecular Interactions and Bindings between Cyclic Peptide and Inhibit Polymerase A and B1 (PAC-PB1N) H1N1 [PDF]

open access: yes, 2015
The influenza/H1N1 virus has caused hazard in the public health of many countries. Hence, existing influenza drugs could not cope with H1N1 infection due to the high mutation rate of the virus. In this respect, new method to block the virus was devised. The polymerase PAC-PB1N enzyme is responsible for the replication of H1N1 virus.
arxiv   +1 more source

Cardiovascular disease management in people with diabetes outside North America and Western Europe in 2006 and 2015 [PDF]

open access: yes, 2018
Aim: Optimal treatment of cardiovascular disease is essential to decrease mortality among people with diabetes, but information is limited on how actual treatment relates to guidelines.
Bahendeka, S.   +18 more
core   +3 more sources

Prescription pattern of antihypertensive drugs in Family Practice Clinics at Jordan University Hospital

open access: yesMedicine Science, 2013
The present study represents the current prescribing trend for antihypertensive drugs in family medicine clinics at Jordan University Hospital in Jordan. The study sample involved 416 male and female hypertensive Jordanian patients.
Essam Al-Drabah   +3 more
doaj   +1 more source

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