Results 111 to 120 of about 268,538 (298)
Italian Journal of Medicine, 2020 This study aims to assess the effect of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor inhibitors (ARBs) on the course of COVID-19.
Gian Paolo Anzola +15 more
doaj +1 more source
Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders [PDF]
, 2016 Major depressive and bipolar disorders predispose to atherosclerosis, and there is accruing data from animal model, epidemiological, and genomic studies that commonly used antihypertensive drugs may have a role in the pathogenesis or course of mood ...
Boal, Angela H. +6 more
core +1 more source
Management of renin-angiotensin system inhibitors prior to major surgery: insights from the STOP-or-NOT trial. [PDF]
Strong recommendations on how to manage renin-angiotensin system inhibitors, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, before surgery are lacking because of a lack of evidence, which is mostly limited to data ...
Gayat, Etienne, Legrand, Matthieu
core +1 more source
Resistance proof, folding-inhibitor drugs [PDF]
, 2002 Conventional drugs work, as a rule, by inhibiting the enzymatic activity of specific proteins, capping their active site. In this paper we present a model of non- conventional drug design based on the inhibiting effects small peptides obtained from segments of the protein itself have on the folding ability of the system.
arxiv +1 more source
Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling [PDF]
, 2014 The renin angiotensin system (RAS) is integral to cardiovascular physiology, however, dysregulation of this system largely contributes to the pathophysiology of cardiovascular disease (CVD).
Akishita +123 more
core +1 more source
Investigating the robustness of the classical enzyme kinetic equations in small intracellular compartments [PDF]
BMC Systems Biology 2009, 3:101, 2009 Classical descriptions of enzyme kinetics ignore the physical nature of the intracellular environment. Main implicit assumptions behind such approaches are that reactions occur in compartment volumes which are large enough so that molecular discreteness can be ignored and that molecular transport occurs via diffusion.
arxiv
American Journal of Cardiovascular Drugs, 2014 The renin–angiotensin–aldosterone system plays a major role in the pathophysiology of hypertension and closely related cardio- and cerebrovascular events.
C. Dézsi
semanticscholar +1 more source
Optimal management of sarcopenia [PDF]
, 2010 Sarcopenia is the progressive generalized loss of skeletal muscle mass, strength, and function which occurs as a consequence of aging. With a growing older population, there has been great interest in developing approaches to counteract the effects of ...
Burton, Louise A., Sumukadas, Deepa
core +5 more sources
Intraspecific and monotone enzyme catalysis with oscillatory substrate and inhibitor supplies [PDF]
Enzyme catalysis in reactors for industrial applications usually require an external intervention of the species involved in the chemical reactions. We analyze the most elementary open enzyme catalysis with competitive inhibition where a time-dependent inflow of substrate and inhibitor supplies is modeled by almost periodic functions.
arxiv +1 more source
Arquivos Brasileiros de Cardiologia, 2000 OBJECTIVE: To evaluate the behavior of blood pressure during exercise in patients with hypertension controlled by frontline antihypertension drugs. METHODS: From 979ergometric tests we retrospectively selected 49 hipertensive patients (19 males). The age
Carreira Maria Angela Magalhães de Queiroz +4 more
doaj