Results 121 to 130 of about 109,906 (243)

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Prenatal exposure to antihypertensive medication: A systematic review of neurodevelopmental and educational outcomes

JCPP Advances, EarlyView.
This systematic review investigated the association of prenatal exposure to antihypertensive medication with longer‐term poor neurodevelopmental outcomes by evaluating the findings from existing literature. We undertook a systematic review of previous studies looking specifically at neurodevelopmental outcomes in children.
Shrifah Alkhalaf, Sarjit Singh, Jill P. Pell, Scott M. Nelson, Daniel F. Mackay, Michael Fleming   +5 more
wiley   +1 more source

Angiotensin-Converting Enzyme Inhibitors, Angiotensin II Receptor Blockers, and the Risk of Acute Pancreatitis: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Alves C, Costa B, Penedones A, Mendes D, Batel Marques F.   +4 more
europepmc   +1 more source

Response and survival of dogs with proteinuria (UPC > 2.0) treated with angiotensin converting enzyme inhibitors. [PDF]

J Vet Intern Med, 2023
Fulton EA, McBrearty AR, Shaw DJ, Ridyard AE.   +3 more
europepmc   +1 more source

Sacubitril/Valsartan Ameliorates Inflammation and Oxidative Stress in Hypertensive Heart Disease by Upregulating CAMKK2 Protein and Modulating the AMPK/AKT/GSK‐3β Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sacubitril/valsartan (Sac/Val) has emerged as an effective compound with myocardium‐protective functions in experimental and clinical trials for heart failure. This study investigated the function of Sac/Val in hypertensive heart disease (HHD) and explored the underlying mechanism.
Yan‐Jun Yang, Jiu‐Sheng Li
wiley   +1 more source

Angiotensin-converting enzyme inhibitors for aortic stenosis: a drug-target Mendelian randomization study. [PDF]

Int J Cardiol Heart Vasc
Ciofani JL, Han D, Woolf B, Gill D, Allahwala UK, Bhindi R.   +5 more
europepmc   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu, Xi‐Xi Chen, Gui‐Hua Wei, Feng Li, Hai‐Yan Zong   +4 more
wiley   +1 more source

Angiotensin-Converting Enzyme Inhibitors to Prevent Liver Fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease: Scientific Speculation or an Opportunity to Improve Real Clinical Practice? [PDF]

Int J Mol Sci
Seidita A, Buscemi C, Di Liberto D, Pistone M, Maestri S, Cavallo G, Cosenza S, Spagnuolo G, Giuliano A, Carlisi D, Pratelli G, Mandreucci F, Carroccio A.   +12 more
europepmc   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors Versus Angiotensin Receptor Blockers: Multidatabase Target Trial Emulation Studies. [PDF]

Hypertension
Xie C, Chen R, Zhou S, Lin Y, Liu J, Su L, Pang M, Guo Z, Luo F, Chen L, Kong Y, Nie S.   +11 more
europepmc   +1 more source