Results 21 to 30 of about 109,906 (243)

Effect of ACE Inhibitors, ARBs, and Other Antihypertensive Drugs on Hypertensive Patients with COVID-19 Infection

Novelty in Biomedicine
Background: To investigate differences in disease severity and outcomes among COVID-19 patients with a history of hypertension using angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and other antihypertensive drugs.
Seyedpouzhia Shojaei, Sara Nooraeen, Zahra Soroureddin, Meghdad Sedaghat, Padideh Ansar, Sadaf Rassouli, Mehdi Goudarzi, Mehrdad Haghighi   +7 more
doaj   +1 more source

Renin-angiotensin-aldosterone system inhibitors – a realm of confusion in COVID-19

Journal of Ideas in Health, 2021
Currently, there is a persisting dispute regarding the renin-angiotensin-aldosterone-system (RAAS) inhibitors' safety of use in COVID-19 pandemics. On one side, RAAS inhibitors appear to determine an overexpression of ACE2, the receptor of SARS-CoV-2 ...
Angela Madalina Lazar
doaj   +1 more source

Variation of Concentrations of Angiotensin II, AngiotensinConverting Enzyme and Matrix Metalloprotease-9 in Tears and Serum of Patients with Diabetic Retinopathy

Oftalʹmologiâ, 2020
Diabetic retinopathy (DR) is becoming more and more widespread disease. Investigation of local changes of metabolic pathways in the eye improves our knowledge about diabetic retinopathy pathogenesis and provide perspective for the development of new ...
V. V. Neroev, N. B. Chesnokova, T. A. Pavlenko, T. D. Okhotsimskaya, O. V. Beznos, V. A. Fadeeva, S. V. Struchkova   +6 more
doaj   +1 more source

Postoperative angioedema induced by angiotensin-converting enzyme inhibitor: case report [PDF]

Revista Brasileira de Anestesiologia, 2019
Background and objectives: Angioedema is a potentially fatal condition that may occur at any time in the perioperative period. It may result from histamine release, hypersensitivity reaction to drugs, or be triggered by bradykinin, in non-allergic ...
Flora Margarida Barra Bisinotto, Beatrice Cavalcanti Seabra, Fernando B. Prata Lóes, Laura Bisinotto Martins, Luciano Alves Matias da Silveira   +4 more
doaj   +3 more sources

Difference in Medication Adherence Between Patients Prescribed a 30‐Day Versus 90‐Day Supply After Acute Myocardial Infarction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Evidence‐based medication adherence rates after a myocardial infarction are low. We hypothesized that 90‐day prescriptions are underused and may lead to higher evidence‐based medication adherence compared with 30‐day fills. Methods and Results
Jennifer A. Rymer, Eileen Fonseca, Durgesh D. Bhandary, Deepa Kumar, Naeem D. Khan, Tracy Y. Wang   +5 more
doaj   +1 more source

Influence of renin‐angiotensin‐aldosterone system inhibitors on plasma levels of angiotensin‐converting enzyme 2

ESC Heart Failure, 2021
Aims Concern has been raised that treatment with angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers may increase the expression of angiotensin‐converting enzyme 2 (ACE2), which acts as the entry receptor for SARS‐CoV‐2, and lead ...
Tobias Zimmermann, Joan Elias Walter, Pedro Lopez‐Ayala, Ivo Strebel, Melissa Amrein, Michael Koechlin, Ursina Honegger, Christian Mueller, BASEL VIII Investigators   +8 more
doaj   +1 more source

Enalaprilat and losartan decrease erythroid precursors frequency in cells from patients with polycythemia vera

Hematology, 2023
Objective: Polycythemia Vera (PV) is a myeloproliferative neoplasm characterized by the overproduction of red blood cells. First-line therapies are directed at lowering hematocrit levels. After the discovery of a mutation in the Janus kinase 2 (JAK2V617F)
Angela Bozza, Martina Bernardi, Daniela Catanzaro, Katia Chieregato, Anna Merlo, Giuseppe Astori   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The effects of angiotensin-converting enzyme inhibitors on peritoneal protein loss and solute transport in peritoneal dialysis patients

Clinics, 2012
OBJECTIVE: The objective of this study was to examine the effects of angiotensin-converting enzyme inhibitors on peritoneal membrane transport, peritoneal protein loss, and proteinuria in peritoneal dialysis patients.
Taner Basturk, Abdulkadir Unsal, Yener Koc, Eren Nezaket, Elbis Ahbap, Tamer Sakaci, Mustafa Sevinc   +6 more
doaj   +1 more source