Results 131 to 140 of about 466,155 (352)

Angiotensin-I-Converting Enzyme and its Relatives [PDF]

, 2011
Angiotensin-I-converting enzyme (ACE) is a monomeric, membrane-bound, zinc- and chloridedependent peptidyl dipeptidase that catalyzes the conversion of the decapeptide angiotensin I to the octapeptide angiotensin II, by removing a carboxy-terminal ...
Riordan, James Francis
core   +1 more source

Trends in first‐line monotherapy and combination therapy for hypertension in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aims Debate remains about the optimal initial treatment strategy for hypertension. Most guidelines recommend first‐line combination therapy for most patients. However, the UK's National Institute for Health and Care Excellence recommends first‐line monotherapy for all patients.
Kyle Johnson, Sarah Beradid, James M. Brophy, Robert W. Platt, Christel Renoux   +4 more
wiley   +1 more source

Mechanisms of the antihypertensive effects of Nigella sativa oil in L-NAME-induced hypertensive rats

Clinics, 2015
OBJECTIVES: This study was conducted to determine whether the blood pressure-lowering effect of Nigella sativa might be mediated by its effects on nitric oxide, angiotensin-converting enzyme, heme oxygenase and oxidative stress markers.
Kamsiah Jaarin, Wai Dic Foong, Min Hui Yeoh, Zaman Yusoff Nik Kamarul, Haji Mohd Saad Qodriyah, Abdullah Azman, Japar Sidik Fadhlullah Zuhair, Abdul Hamid Juliana, Yusof Kamisah   +8 more
doaj   +1 more source

An experimental medicine protocol for exploring the haemodynamic effects of dual agonism at the glucagon‐like peptide‐1 and glucagon receptor in healthy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims Glucagon‐like peptide‐1 (GLP‐1) and glucagon dual receptor agonists are in clinical development for a range of metabolic conditions, including type 2 diabetes and obesity. The cardiovascular actions at these receptors are well studied, but less is known about their combination.
James Goodman, Victoria E. Parker, Carmel M. McEniery, Giovanni Di Stefano, Annette Hubsch, Evangelia Vamvaka, Jo Helmy, Fotini Kaloyirou, Navazh Jalaludeen, Peter Barker, Lutz Jermutus, Joseph Cheriyan, Philip Ambery, Ian B. Wilkinson   +13 more
wiley   +1 more source

AKTIVIITAS ANTIOKSIDAN ANTIHIPERLIPIDEMIA DAN ANTIHIPERTENSI DARI EKSTRAK ETANOL DAUN KEDABU (Sonneratia ovata. Backer)

JIIS: Jurnal Ilmiah Ibnu Sina
            Kedabu (Sonneratia ovata. Backer) merupakan salah satu jenis mangrove dari genus Sonneratia dengan kandungan tinggi flavonoid yang berpotensi sebagai antioksidan. Kandungan flavonoid dalam tumbuhan kedabu meliputi sonnerphenolic, vanillin, (-
Danang Raharjo, Anna Fitriawati, Muhhamad Aminnulloh   +2 more
doaj   +1 more source

Aktivitas Antioksidan Danangiotensin-I Converting Enzyme Inhibitor oleh Yogurt dengan Ekstrak Daun Ficus Glomerata Roxb [PDF]

, 2017
Ficus glomerata Roxb has been known to have flavonoids. Flavonoids in plant are known for their antioxidant activity and ability to the Angiotensin Converting Enzyme I- inhibitor.
Marsono, Y. (Yustinus), Rahayu, E. S. (Endang), Utami, T. (Tyas), Wulandani, B. R. (Baiq)   +3 more
core  

Chemically Synthesized LRAD3‐D1 Interacts with N‐Terminal Domain of SARS‐CoV‐2 Spike Protein

ChemBioChem, EarlyView.
Chemical synthesis, calcium‐templated in‐vitro folding and competitive ELISA assay reveal that only domain 1 of the LRAD3 ectodomain interacts with the severe acute respiratory syndrome‐related corona virus 2 (SARS‐CoV‐2) spike NTD, while domains 2 and 3 do not, providing valuable insight into ACE2‐independent viral entry pathways that may contribute ...
Mrinmoy Jana, Rathina Delipan, Arighna Sarkar, Sreejith Raran‐Kurussi, Rajesh P. Ringe, Kalyaneswar Mandal   +5 more
wiley   +1 more source

Effectiveness of Angiotensin-Converting Enzyme Inhibitors in Pediatric Patients with Mid to Severe Aortic Valve Regurgitation [PDF]

, 2018
The long-term benefit of angiotensin-converting enzyme inhibitors in pediatric patients with aortic valve regurgitation is under consideration.
Bauersfeld, Urs, Gisler, Fabian, Harpes, Paul, Knirsch, Walter   +3 more
core  

Minimum Lumen Area Indexed to Left Ventricular Mass to Identify Functionally Significant Left Main Coronary Stenoses

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background and Aim Diagnosing significant left main coronary artery (LMCA) stenoses based on anatomical criteria remains challenging. The ARMYDA FINISH multicenter study evaluated whether indexing intravascular ultrasound (IVUS)‐derived minimum lumen area (MLA) provides greater diagnostic accuracy than unindexed MLA for detecting ...
Giuseppe Patti, Leonardo Grisafi, Marco Mennuni, Luca Cumitini, Manuel Bosco, Domenico D'Amario, Martina Solli, Roberta Rosso, Matilde Villa, Gioel Gabrio Secco, Edoardo Elia, Giuseppe Colonna, Vincenzo Galiffa   +12 more
wiley   +1 more source

Effect of the inhibitor of angiotensin i converting enzyme on endocrine function and renal perfusion in haemorrhagic shock [PDF]

, 1977
Maki Yamashita, Tsutomu Oyama, Tsuyoshi Kudo   +2 more
openalex   +1 more source