Results 301 to 310 of about 466,155 (352)

COVID-19 and Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers: What Is the Evidence?

Journal of the American Medical Association (JAMA), 2020
Coronavirus disease 2019 (COVID-19) is a current pandemic infection caused by a positive-sense RNA virus named the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The particularly infectious capacity of the virus, along with mortality rates
A. Patel, A. Verma
semanticscholar   +1 more source

The angiotensin converting enzyme (ACE)

The International Journal of Biochemistry & Cell Biology, 2003
Angiotensin converting enzyme 1, found widely throughout the animal kingdom, is an integral membrane bound protein whose active sites are directed to the extracellular spaces. Two isoforms are expressed in mammals, a single domain germinal isoform required for male fertility, and a double domain somatic isoform which has a key role in the renin ...
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Angiotensin converting enzyme inhibitors

Pharmaceutisch Weekblad Scientific Edition, 1982
Inhibition of angiotensin converting enzyme (ACE) in patients suffering from renovascular hypertension results in lowering of the blood-pressure. The development of captopril, an orally active ACE inhibitor and the structure-activity relationship of captopril analogues are described.
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Angiotensin-Converting Enzyme Inhibitors

AACN Advanced Critical Care, 1992
The angiotensin-converting enzyme (ACE) inhibitors available today include Captopril (Capoten), enalapril (Vasotec), enaloprilat (Vasotec IV), lisinopril (Prinivil, Zestril), benazepril (Lotensin), fosinopril (Monopril), and ramipril (Atace). These drugs are used in the treatment of hypertension and congestive heart failure.
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Angiotensin and angiotensin-converting enzyme inhibitors

Baillière's Clinical Anaesthesiology, 1994
Summary The advent of the increasing use of different angiotensin-converting enzyme (ACE) inhibitors for the treatment of hypertension and cardiac failure has resulted in intense interest in the renin-angiotensin system (RAS) and its manipulation for therapeutic gain, and thus more patients will present for surgical anaesthesia while on maintenance ...
Berend Mets, Edward D. Miller
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Angiotensin-converting enzyme

Angiotensin Converting Enzyme (ACE), is a zinc containing metallopeptidase, best known for its role in the conversion of Ang I in the active peptide Ang II, which plays a pivotal role in the blood pressure (BP) regulation trough the Renin Angiotensin System (RAS). In the last decades RAS has been deeply studied in all its aspects and implications.
Arrighi, F., Berrino, E., Secci, D.
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Angiotensin‐Converting Enzyme in Sarcoidosis

Acta Medica Scandinavica, 1979
ABSTRACT Using a spectrophotometric assay with l‐hippuryl‐l‐histidyl‐l‐leucine as substrate, s‐angio‐tensin‐converting enzyme (SACE) was determined in 85 sarcoidosis patients, 116 healthy controls and 150 patients with various non‐sarcoid diseases. The controls showed no sex or age variation and had SACE levels of 24.4±6.2 U/ml (mean ± 1 S.D.), giving ...
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Angiotensin-Converting Enzyme Inhibition, Angiotensin, and Cognition

Journal of Cardiovascular Pharmacology, 1992
In these studies, we have investigated possible cognition-enhancing effects of angiotensin-converting enzyme (ACE) inhibition, and putative neurochemical correlates for these actions. In a mouse habituation model, ACE inhibitors improved basal performance and antagonized scopolamine-induced deficits.
Nicholas M. Barnes, M. E. Kelly, J. Coughlan, T J Williams, Robert J. Naylor, Brenda Costall, J.M. Barnes, D. M. Tomkins   +7 more
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Angiotensin-Converting Enzyme Inhibitors

Medical Clinics of North America, 1987
In summary, ACE inhibitors are effective in reducing blood pressure as initial therapy in some hypertensive patients and in combination with diuretics and other agents in virtually all hypertensives. ACE inhibitors are uniquely advantageous because of their favorable hemodynamic effects, the lack of adverse metabolic effects, and their ability to ...
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Angiotensin-converting enzyme inhibitors

2001
Publisher Summary Angiotensin-converting enzyme (ACE) inhibitors were first studied clinically in the 1970s. ACE inhibitors were discovered by taking advantage of previous basic research on the physiology of sodium, potassium, and water homeostasis and blood pressure regulation, in a reciprocal way ACE have also advanced research in this field, and ...
Arthur A. Patchett, Joël Ménard
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