Results 311 to 320 of about 466,155 (352)

Glucocorticoid induction of angiotensin converting enzyme

Agents and Actions, 1986
Angiotensin converting enzyme (ACE) converts angiotensin I (Angio I) to angiotensin II (Angio II) and inactivates bradykinin (BK). Glucocorticoids in the physiological range increase ACE in rabbit alveolar macrophages and bovine endothelial cells in culture.
IALENTI, ARMANDO, CALIGNANO, ANTONIO, CARNUCCIO, ROSA, M. Di Rosa   +3 more
openaire   +4 more sources

Renin and angiotensin converting enzyme in elasmobranchs

General and Comparative Endocrinology, 1992
Renin-like activity (RLA) and angiotensin I converting enzyme-like activity (ACELA), the two key enzymes of the renin-angiotensin system (RAS), were sought in the elasmobranch Scyliorhinus canicula. Renal extracts were desalted in a G-25 and eluted in a G-100 Sephadex column (calibration 15,000-70,000).
L.B. O'Toole, L.B. O'Toole, L.B. O'Toole, Biancamaria Uva, Neil Hazon, Neil Hazon, Neil Hazon, I. W. Henderson, I. W. Henderson, I. W. Henderson, P. Ghiani, P. Ghiani, P. Ghiani, M. A. Masini, M. A. Masini, M. A. Masini   +15 more
openaire   +5 more sources

ACUTE AND CHRONIC EFFECTS OF ANGIOTENSIN‐CONVERTING ENZYME INHIBITORS ON TISSUE ANGIOTENSIN‐CONVERTING ENZYME

Clinical and Experimental Pharmacology and Physiology, 1992
SUMMARY1. The effects of angiotensin‐converting enzyme (ACE) inhibitors on the tissue ACE were assessed by quantitative in vitro autoradiography after acute and chronic administrations of the drugs.2. Following acute administration of lisinopril, perindopril or benazepril, ACE was markedly inhibited in the lung, kidney and blood vessels but not in the ...
Rose Perich, Colin I. Johnston, Siew Yeen Chai, Bruce Jackson, Frederick A.O. Mendelsohn   +4 more
openaire   +3 more sources

2 Inhibitiors of Angiotensin-Converting Enzyme

1980
Publisher Summary This chapter focuses on the development, mechanism of action, and biological activity of two distinct classes of therapeutically useful inhibitors of angiotensin-converting enzyme: the snake venom peptides and a newly developed class of orally active inhibitors that were designed for specific binding to the active site of this ...
David W. Cushman, Miguel A. Ondetti
openaire   +3 more sources

Assay of Tissue Angiotensin Converting Enzyme

Journal of Cardiovascular Pharmacology, 1989
The distinction between a circulating renin-angiotensin system and a tissue renin-angiotensin system led us to determine tissue angiotensin converting enzyme (ACE) activity. This study establishes the experimental conditions for a good reproducibility of the fluorimetric assay of ACE and describes the use of [3H]ramiprilat to characterize ACE ...
Jean-Louis Imbs, Jean-Jacques Helwig, Mariette Barthelmebs, C. Coquard, C. Welsch, Michèle Grima, E. M. Giesen   +6 more
openaire   +3 more sources

Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients.

New England Journal of Medicine, 2000
S. Yusuf, P. Sleight, J. Pogue, J. Bosch, R. Davies, G. Dagenais   +5 more
semanticscholar   +1 more source

The Future of Angiotensin-Converting Enzyme Inhibitors

Journal of Cardiovascular Pharmacology, 1985
After a brief introduction summarizing their historical development and the classification of angiotensin-converting enzyme inhibitors by chemical structure, the considerations involved in developing new and improved drugs of this pharmacologic class are discussed.
openaire   +3 more sources

Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).

Journal of the American Medical Association (JAMA), 2002
C. Furberg, J. Wright, B. Davis, J. Cutler, M. Alderman, H. Black, W. Cushman, R. Grimm, L. Haywood, F. Leenen, S. Oparil, J. Probstfield, P. Whelton, C. Nwachuku, D. Gordon, M. Proschan, Paula Einhom, C. Ford, L. Piller, I. K. Dunn, D. Goff, S. Pressel, Judy Bettencourt, Barbara DeLeon, Lara M. Simpson, J. Blanton, T. Geraci, Sandra M. Walsh, C. Nelson, Mahboob Rahman, Anne Juratovac, R. Pospíšil, L. Carroll, Sheila Sullivan, J. Russo, G. Barone, Rudy Christian, S. Feldman, T. Lucente, D. Calhoun, Kimo Jenkins, Peggy McDowell, Janice Johnson, C. Kingry, J. Alzate, K. Margolis, Leslie Ann Holland-Klemme, B. Jaeger, J. Williamson, G. Louis, Pamela Ragusa, A. Williard, R. L. Ferguson, J. Tanner, J. Eckfeldt, R. Crow, J. Pelosi   +56 more
semanticscholar   +1 more source

Enzymes in Sarcoidosis: Angiotensin-Converting-Enzyme (ACE)

Clinics in Laboratory Medicine, 1989
Measurement of serum angiotensin-converting-enzyme (SACE) is the most useful test for diagnosing and monitoring disease activity in sarcoidosis. Because elevated levels of SACE are not specific for sarcoidosis, other conditions in which SACE levels are also elevated are examined.
openaire   +3 more sources

The Leech Angiotensin‐Converting Enzyme

Annals of the New York Academy of Sciences, 1998
Michel Salzet, George B. Stefano, Virginie Laurent   +2 more
openaire   +3 more sources