Aldosterone synthase inhibitors for hypertension: A breakthrough facing barriers to adoption. [PDF]
Laffin LJ, Nissen SE.
europepmc +1 more source
Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto +13 more
wiley +1 more source
A Retrospective Analysis of Human Angiotensin II Receptor Blockers (ARB) Pharmacokinetics, Dosages and C<sub>max</sub> Values for the Experimental Modelling of Pleiotropic and Supratherapeutic Activities. [PDF]
Evans A, Bernatchez P.
europepmc +1 more source
Nonpeptide Angiotensin II Receptor Antagonists: Studies With EXP9270 and DuP 753
P. Wong +7 more
semanticscholar +1 more source
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu +13 more
wiley +1 more source
The immunomodulatory potential of bradykinin signaling in autoimmune conditions. [PDF]
Szaryńska M, Olejniczak-Kęder A.
europepmc +1 more source
Current Status of Kidney Xenotransplantation in Basic Research
Kidney xenotransplantation is a potential solution to the organ shortage for end‐stage kidney disease. This review systematically elaborates on the application advances of donor pig gene editing technologies, the molecular mechanisms and regulatory strategies of xenogeneic immune rejection, and the optimization approaches of immune compatibility ...
Yu Luo, Bingzhuo Liu, Weijie Lai
wiley +1 more source
Association between angiotensin receptor-neprilysin inhibitor use and clinical outcomes in patients with heart failure: a 1-year prospective cohort study from Jordan. [PDF]
Odeh RS +5 more
europepmc +1 more source
The combination of cardiac resynchronization therapy and pulmonary artery banding was associated with substantial improvement in advanced heart failure infants with left ventricular dilated cardiomyopathy and left bundle branch block. Most patients exhibited marked improvement in clinical status and ventricular function, along with a reduction in QRS ...
Min Zeng +8 more
wiley +1 more source
Association Between Pre-hospital Medication Use and Outcomes in Patients Hospitalized for COVID-19 Pneumonia: A Multicenter Observational Study in the Netherlands. [PDF]
Li L +11 more
europepmc +1 more source

