Results 41 to 50 of about 1,818,982 (242)

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Alpha Kappa Alpha EAF Awards luncheon program, July 15, 2014

open access: yes, 2014
This program for the Educational Advancement Foundation (EAF) Awards luncheon given by the Alpha Kappa Alpha sorority notes the sequence of events, leaders of the EAF, and sponsors for the gathering.Archival master image scanned in reflective mode as 48 ...
Alpha Kappa Alpha
core   +1 more source

Correlation and predictability of ocular aberrations and the visual outcome after quadrifocal intraocular lens implantation: a retrospective longitudinal study

open access: yesBMC Ophthalmology, 2019
Background To evaluate the correlating and predicting factors of visual outcome after implantation of newly developed diffractive quadrifocal intraocular lens (IOL). Methods A retrospective longitudinal study was conducted.
Chia-Yi Lee   +5 more
doaj   +1 more source

Radiographic Indirect Parameters for First Metatarsal Rotation do not Correspond to Real Measurements in Hallux Valgus

open access: yesFoot & Ankle Orthopaedics, 2022
Category: Midfoot/Forefoot; Bunion Introduction/Purpose: Subjective radiographic findings are commonly used in Hallux Valgus (HV) to dictate deformity aspects and surgical treatment. Head roundness, distal metatarsal metaphyseal angle (DMMA) and sesamoid
Nacime S. Mansur MD   +9 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

What Are the Reference Values and Associated Factors for Center-edge Angle and Alpha Angle? A Population-based Study. [PDF]

open access: yes, 2018
BACKGROUND The available evidence regarding normal ranges for the center-edge angle and the alpha angle derives from a few small studies, and associated factors such as sex and anthropometric factors have not been well evaluated.
Jens-Peter Kühn   +19 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Alpha-1 antitrypsin deficiency gut microbiome

open access: yes, 2020
This dataset contains 16S rRNA Illumina MiSeq sequenced samples used in our gut microbiome study in individuals with alpha-1 antitrypsin deficiency (AATD) and controls (non-AATD)
Kirst, ME (University of Florida)
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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