Results 91 to 100 of about 40,772 (257)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

British angling flies

open access: yes
Cover title: List of angling flies, &c.Mode of access ...
Theakston, Michael., Michael. Theakston
core   +1 more source

Baseline data of the marine recreational fisheries in the NW Mediterranean Sea: finding the variable that drives the catch

open access: yesFrontiers in Marine Science
Recreational fishing is an increasingly popular leisure activity on a global scale, with catches that may surpass those of commercial fisheries. However, the lack of comprehensive and standardized data hinders accurate assessment of its ecological impact.
Marta Pujol-Baucells   +13 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

Ranking New Zealand river values – a novel approach to managing the ‘chalk and cheese’ problem [PDF]

open access: yes
In New Zealand, regional councils have the task of sustainably managing rivers and their flows. In trying to achieve this task they face enormous challenges including the need to allocate flows amongst often highly disparate in- (e.g., angling, kayaking,
Hughey, Kenneth F.D.
core  

Pekerja Anak, Upaya Implementasi Konvensi Hak Anak di Indonesia, Faktor Penyebab dan Metode Pencegahannya

open access: yesLex Librum, 2018
Faktor-faktor yang menyebabkan anak Indonesia terutama yang tinggal di kota Palembang terkategori anak jalanan, pengemis dan gelandangan adalah disebabkan oleh hal-hal sebagai berikut: a.
Derry Angling Kesuma
doaj  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

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