Results 91 to 100 of about 45,951 (270)

Anhedonia, depression, and symptom severity in obsessive-compulsive disorder

Journal of Affective Disorders Reports
Background: Anhedonia, the diminished capacity to experience pleasure, is a transdiagnostic symptom of growing interest across psychiatric conditions.
Brian A. Zaboski, Katherine Jones, Christopher Pittenger, Elizabeth F. Mattera   +3 more
doaj   +1 more source

Classification of social anhedonia using temporal and spatial network features from a social cognition fMRI task

, 2019
Previous studies have suggested that the degree of social anhedonia reflects the vulnerability for developing schizophrenia. However, only few studies have investigated how functional network changes are related to social anhedonia.
Hinrich, Jesper L, Chan, Raymond C K, Hinrich, Jesper Løve, Chan, Raymond C. K., Madsen, Kristoffer H., Krohne, Lærke Gebser, Moerup, Morten, Mørup, Morten, Hinrich, Jesper L., Wang, Yi, Yi Wang, Madsen, Kristoffer H, Krohne, Laerke Gebser, Jesper L. Hinrich, Madsen, Kristoffer Hougaard, Chan, Raymond CK, Morten Moerup, Laerke Gebser Krohne, Raymond C. K. Chan, Kristoffer H. Madsen   +19 more
core   +1 more source

Individuals with psychometric schizotypy show similar social but not physical anhedonia to patients with schizophrenia

, 2014
Very few studies have examined physical and social anhedonia across the spectrum of schizophrenia. In the present study, we recruited three groups of participants (n=84 in each group): patients with schizophrenia, schizotypy and non-schizotypy as ...
Wang, Yi, Zhang, Qi, Zhao, Qing, Chan, Raymond C. K., Zou, Lai-quan, Cheung, Eric F. C., Tan, Shu-ping, Hong, Xiao-hong, Lui, Simon S. Y., Yan, Chao   +9 more
core   +1 more source

Brain network localization of anhedonia

Translational Psychiatry
Anhedonia, encompassing a broad spectrum of deficits in reward processing, is highly prevalent in major depressive disorder (MDD) and constitutes one of its core symptoms.
Chenglong Liu, Yu Song, Xufeng Zhao, Zhili Wang, Liping Yan, Yongqiang Yu, Jiajia Zhu   +6 more
doaj   +1 more source

An Interdisciplinary Review of the Gaslighting Literature and Future Research Agenda

Journal of Organizational Behavior, EarlyView.
ABSTRACT Gaslighting is increasingly discussed in organizational contexts, yet its meaning, boundaries, and process remain unclear within management and organizational scholarship. Although research on gaslighting has expanded across multiple disciplines, existing work is conceptually fragmented and difficult to integrate, limiting cumulative theory ...
Paula A. Kincaid, Samantha C. O. Stalion
wiley   +1 more source

The effects of working memory training on enhancing hedonic processing to affective rewards in individuals with high social anhedonia

, 2016
Anhedonia is a core feature of the negative symptoms of schizophrenia and is less responsive to anti psychotic medication. Little is known whether anhedonia could be alleviated by cognitive training.
Li, Xu, Chan, Raymond C. K., Shi, Hai Song, Zou, Lai Quan, Xiao, Ya Hui, Yang, Zhuo Ya, Chan, Raymond C.K., Li, Huan-Huan, Cheung, Eric F.C., Xiao, Ya-Hui, R.C.K. Chan, Li, Huan Huan, Zou, Lai-Quan, Cheung, Eric F. C., Shi, Hai-Song, Yang, Zhuo-Ya, Lui, Simon S. Y., Lui, Simon S.Y.   +17 more
core   +1 more source

Apathy in Lewy Body Disorders: A Position Paper

Movement Disorders, EarlyView.
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky, Lidia Bojtos, Milica G. Kramberger, Elisa Mantovani, Iulia Murasan, Jose‐Alberto Palma, Karolina Poplawska‐Domaszewicz, Anna Sauerbier, Kallol Ray Chaudhuri, Per Odin, Daniel Weintraub, Anette Schrag, Cristian Falup‐Pecorariu   +12 more
wiley   +1 more source

Neurobiological mechanisms of anhedonia

Dialogues in Clinical Neuroscience, 2008
Anhedonia refers to the reduced ability to experience pleasure, and has been studied in different neuropsychiatric disorders. Anhedonia is nevertheless considered as a core feature of major depressive disorder, according to DSM-IV criteria for major depression and the definition of melancholic subtype, and regarding its capacity to predict ...
openaire   +3 more sources

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

ANHEDONIA IN SCHIZOPHRENIA: MINI-REVIEW [PDF]

, 2019
The perception of reward exerts a powerful influence on human behavior. While anhedonia might occur in healthy individuals, its prevalence and severity are much higher in psychiatric patients, particularly those with depression and schizophrenia ...
Tudor, Lucija, Jakšić, Nenad Jakšić, Kosanović Rajačić, Biljana, Pivac, Nela, Madžarac, Zoran, Šimunić, Lucija Šimunić, Kudlek Mikulić, Suzan, Šagud, Marina, Vuksan-Ćusa, Bjanka, Stefanović, Ivana, Šimunović Filipčić, Ivona, Mihaljević Peleš, Alma, Jezernik, Dejana   +12 more
core   +1 more source