Results 91 to 100 of about 175,197 (281)

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Two-way facilitated transport membrane for CO2 separation with synergy of nucleophilic addition and π-complexing reactions: Molecular simulation and experimental study [PDF]

علوم و تکنولوژی پلیمر
Hypothesis: PEBA, also known as polyether-block-amide, has emerged as a highly favorable polymer material for the production of CO2 separator membranes. The membranes made from PEBA rely on the solution-diffusion mechanism for separation.
Mahdi Elyasi Kojabad, Parya Amirabedi, Masoud Dorfeshan   +2 more
doaj   +1 more source

Ti–Pd Alloys as Heterogeneous Catalysts for Hydrogen Autotransfer Reaction and Catalytic Improvement by Hydrogenation Effects [PDF]

, 2019
Ti−Pd alloys were investigated as heterogeneous catalysts for hydrogen autotransfer reactions. This is the first reported study of alloys as catalysts for hydrogen‐borrowing reactions using alcohols.
Kondo Ryota, Obora Yasushi, Suzuki Takeyuki, Takahashi Yuya, Takeshita Hiroyuki T, Utsunomiya Masayoshi, 大洞 康嗣, 竹下 博之, 近藤 亮太   +8 more
core   +1 more source

Synthesis and characterisation of controllably functionalised polyaniline nanofibres [PDF]

, 2009
A novel method for functionalising solution based polyaniline (PAni) nanofibres is reported whereby the degree of side-chain attachment can be controllably altered.
Acevedo, Acevedo, Baker, Bao, Barbero, Barbero, Belzig, Blake, Byrne, Castro, Chiou, Chiou, Ci, Cui, Dermot Diamond, Drury, Emer Lahiff, Gordon G. Wallace, Goutev, Han, Huang, Huang, Hussain, Inoue, Jiang Yue, Krishnakumar, Lahiff, Li, Li, Liu, Luo, MacDiarmid, Masdarolomoor, Masdarolomoor, Mazeikiene, Moller, Nikoobakht, Roh, Salavagione, Small, Tran, Trevor Woods, Tseng, Virji, Virji, Virji, Virji, Werner Blau, Xingwei Li, Yasuda   +49 more
core   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Penerapan sablon pada finishing kulit suede

Majalah Kulit, Karet, dan Plastik, 2004
The application of screen printing on suede leather is the method to improve a high fashion of the apparel material. The motif was applied on the flesh or the grain of suede lether by screening method.
Emiliana Kasmudjiastuti, Emi Sulistyo Astuti   +1 more
doaj   +1 more source

MDP25‐VDAC3 Complex Orchestrates Actin Remodeling and Mitochondrial Dynamics to Modulate Innate Immunity in Arabidopsis

Advanced Science, EarlyView.
This study reveals that actin remodeling regulates mitochondrial elongation as a defense strategy in plants. Flagellin perception induces fusion‐dependent elongation, supported by cortical actin bundles, to repair damage and boost ATP and ROS production.
Junxiu Hou, Pengfei Lu, Xuan Cui, Liangfeng Luo, Qing Pan, Jiejie Li   +5 more
wiley   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Process for lowering the dielectric constant of polyimides using diamic acid additives [PDF]

, 1990
Linear aromatic polyimides with low dielectric constants are produced by adding a diamic acid additive to the polyamic acid resin formed by the condensation of an aromatic dianhydride with an aromatic diamine. The resulting modified polyimide is a better
St.clair, Anne K., Stoakley, Diane M.
core   +1 more source

NIR‐Activatable Domino Cascade Catalysis Nanozyme Reactor for Multi‐Mechanism Synergistic Immunotherapy in Bladder Cancer

Advanced Science, EarlyView.
This study presents an intravesical delivery strategy of ferroptosis‐ and immunity‐inducing nanozyme‐loaded thermoresponsive hydrogels (FMCC@PNH) for enhanced bladder cancer therapy. Abstract Current intravesical therapies for bladder cancer after resection are limited by poor tissue penetration, off‐target effects, and insufficient efficacy.
Yongnan Jiang, Qingling Zhang, Yuhan Zhang, Xinlu Yu, Bo Jia, Yulong Dong, Yalong Wu, Kelong Fan, Xinquan Gu, Lei Ji, Wei Jiang, Bin Liu   +11 more
wiley   +1 more source