Results 191 to 200 of about 125,028 (275)

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao   +7 more
wiley   +1 more source

Chemoselective Synthesis of δ-Amino Alcohols from Chiral 1,4-Diols Catalyzed by an NHC-Ir(III) Complex. [PDF]

open access: yesOrg Lett
Silvi E   +5 more
europepmc   +1 more source

Recent Advances in Conductive Rubber Composites: Progress, Challenges, and Emerging Opportunities

open access: yesMacromolecular Rapid Communications, EarlyView.
This study reviews the recent advances in conductive rubber composites, focusing on key aspects such as material selection, conductive mechanisms, interfacial engineering, processing methods, vulcanization strategies, and practical applications. It also discusses current challenges and highlights emerging directions that are shaping the development of ...
Lu Yin   +3 more
wiley   +1 more source

Aniline-induced refractory methemoglobinemia in polytrauma: successful management with erythrocytapheresis. [PDF]

open access: yesInt J Emerg Med
Lečbychová K   +5 more
europepmc   +1 more source

Bright Ferritin for Non‐Invasive MRI Monitoring of the Fate of Transplanted hPSC‐Cardiomyocytes in the Infarcted Rat Heart

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To demonstrate that a recently reported bright ferritin magnetic resonance imaging (MRI) platform can track transplanted human pluripotent stem cell (hPSC)‐derived cardiomyocytes (hPSC‐CMs) longitudinally and on‐demand in the rat heart.
Keyu Zhuang   +12 more
wiley   +1 more source

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

open access: yesChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda   +7 more
wiley   +1 more source

Progress on the Application of Polymers of Intrinsic Microporosity for the Adsorption of Organic Contaminants

open access: yesChemistryOpen, EarlyView.
The pictorial illustration of the applications of polymers of intrinsic microporosity extraordinary porous organic polymers with high surface areas, pore radii, pore volumes, high permeability, high diffusivity, high selectivity, and high thermal stability, as suitable filters or purifiers for water contaminated with pharmaceutical and organic dyes ...
Martins O. Omorogie
wiley   +1 more source

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