Results 131 to 140 of about 1,592,056 (239)

Aniline-Based Hyper-Cross-Linked Polymer–In₂O₃ Composite Boosting CO₂ Epoxide Ring-Opening Reaction Activity without Cocatalysts

Significant efforts have been devoted to develop an efficient catalytic system without the use of cocatalysts for the conversion of CO2 to cyclocarbonate.
Tao Wang (12008), Kunpeng Song (1391251), Sini He (18318195), Yunwen Liao (810653), Bin Xu (10691)   +4 more
core   +1 more source

Substrate‐Selective Inhibition of the SARS‐CoV‐2 Papain‐Like Protease: Inhibition of Hydrolysis of Human Over Viral Substrates

Chemistry – A European Journal, EarlyView.
The SARS‐CoV‐2 papain‐like protease (PLpro) is a medicinal chemistry target. Here we report mass spectrometry assays employing oligopeptide substrates based on the sequences of the viral polyproteins 1a/1ab and on an ISG15‐modified human protein, which enabled the identification of substrate‐selective PLpro inhibitors.
Sakshi Sharma, Peter A. C. Wing, Wojtek Treyde, Shyam Basak, Simeon D. Draganov, Taylah Andrews‐Clark, Eidarus Salah, Petra Lukacik, Claire Strain‐Damerell, Adán Pinto‐Fernández, Martin A. Walsh, Fernanda Duarte, Christopher J. Schofield, Lennart Brewitz   +13 more
wiley   +1 more source

Stereoretentive Nucleophilic Aromatic Substitution Accesses Atropisomeric 4‐Amino‐N‐Arylquinolinium Salts

Chemistry – A European Journal, EarlyView.
Quinolin‐4‐ones were converted to chloroquinolinium salts, allowing formation of axially chiral aminoquinolinium salts via an enantioretentive SNAr reaction with a variety of amine nucleophiles. The salts have a high rotational barrier, with a racemization half‐life of ∼1000s of years.
Darren Holmes, Nia Foster, Saima Ansari, Paul Kavanagh, Paul Dingwall, Peter C. Knipe   +5 more
wiley   +1 more source

Decoding Heptazine Architectures: From Molecular Association to Structural Insight

Chemistry – A European Journal, EarlyView.
A comprehensive study (NMR and theoretical) of three novel heptazine derivatives that self‐assemble into dimers has been conducted, highlighting their versatility as a platform for multifunctional supramolecular and optoelectronic materials. ABSTRACT Heptazine (Hpz) derivatives display remarkable supramolecular organization governed by noncovalent ...
Silvia del Moral, Daniel Barrena‐Espés, Julen Munarriz, Matthias Lehmann, Pilar Romero, José Luis Serrano   +5 more
wiley   +1 more source

Rapid Access to Photoswitchable RNA Binders: Fluorination Enhances Protein Rescue by Exon Inclusion

Chemistry – A European Journal, EarlyView.
An adaptable approach, many light‐switchable RNA binders. We report a versatile strategy for rapidly synthesizing photoswitchable RNA binders. The ligands can target SMN2 pre‐mRNA, restoring the levels of the corresponding protein by exon‐inclusion rescue.
Lei Zhang, Nemanja Djokovic, Alexander Herr, Anna Wacker, Emily Swanson Hay, Daniel Santana, Amanda E. Hargrove, Harald Schwalbe, Katarina Nikolic, Frank Abendroth, Olalla Vázquez   +10 more
wiley   +1 more source

Ni2‐Imido Bispincer Platforms: Cooperative Reactivity Enabled Through Substrate Addition Across a Ni2N Unit

Chemistry – A European Journal, EarlyView.
Ni2 bispincer complexes with an embedded central imido anchor are presented. The bispincer complexes leverage the high basicity of imido ligands to facilitate 1,2 addition of weak B─H and Si─H bonds, resulting in hydrido–amido complexes and resultingly a contortion of a Ni─Ni sigma bond to form an S = 1 species. The 1,2 addition is proposed to serve as
David de los Santos, Kritika Gour, Manar M. Shoshani   +2 more
wiley   +1 more source

Cyclopropylamine‐Derived Distonic Iminium Radicals: Photoinduced Strategies in Chemo‐ and Stereo‐Selective Synthesis

Chemistry – A European Journal, EarlyView.
Cyclopropylamines have emerged as powerful photocatalytic building blocks. Upon light‐induced single‐electron oxidation, they undergo strain‐release ring opening to generate distonic iminium radicals that enable diverse transformations, including ring‐opening functionalization, formal [3 + 2] cycloadditions, radical cascades, and asymmetric bond ...
Maria Chiara Cabua, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +3 more
wiley   +1 more source

Anodic corrosion of copper in presence of aniline derivatives

, 2012
322-330The rates of anodic corrosion of copper plates in different concentrations of phosphoric acid (6, 8, 10, 12 and 14 mol) have been studied by measuring the limiting current of anodic dissolution.
Abaza, Sana F, Seleim, Seleim M, Ahmed, Abdel Moneum M, Ayobe, Eman A   +3 more
core  

Hybrid Macrocyclic Peptides — Synthetic Strategies to Diversify and Cyclize Peptide Libraries in Phage Display Selections

Chemistry – A European Journal, EarlyView.
Hybrid macrocyclic peptides unite genetically encoded peptide libraries with the structural complexity of synthetic small molecules. This Review critically analyzes phage‐compatible cyclization and diversification chemistries, highlights emerging opportunities beyond traditional cysteine‐based approaches, and outlines how future advances may enable the
Titia Rixt Oppewal, Clemens Mayer
wiley   +1 more source

Rhodium‐Catalyzed Synthesis of Enantioenriched α‐Substituted Primary Amines Through Asymmetric Transfer Hydrogenation

Chemistry – A European Journal, EarlyView.
Enantioenriched α‐substituted primary amines are efficiently prepared by rhodium‐catalyzed asymmetric transfer hydrogenation of ortho‐hydroxyaryl N─H imines under mild conditions using a low catalyst loading and ammonium formate as the hydrogen source in high yields (up to 99%) and enantioselectivities (up to 99% ee).
Chonghuo Liu, Guillaume Lefèvre, Qin Yin, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +4 more
wiley   +1 more source