Results 251 to 260 of about 71,285 (330)

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao   +7 more
wiley   +1 more source

Vegetable Oil‐Based Materials for Drug Delivery Systems and Wound Dressings

open access: yesMacromolecular Bioscience, EarlyView.
Renewable resources like vegetable oils are increasingly explored for biomaterial production in biomedical applications. Their monoglycerides and triglycerides inherently possess functions or can be chemically modified to introduce functional groups suitable for polymerization, yielding biomaterials with desirable properties such as flexibility ...
Lucas M. Favre   +2 more
wiley   +1 more source

Synthesis of bio-based N-containing compounds from biomass. [PDF]

open access: yesNatl Sci Rev
Ji J   +5 more
europepmc   +1 more source

Morphological and Computational Analysis of Additively Manufacturable Polyimide Precursors: Implications for Rationally Designing New Polyimide Structures

open access: yesMacromolecular Materials and Engineering, EarlyView.
Multiscale experiments and DFT calculations establish how polyimide precursor choice governs additively manufactured morphology. PMDA/ODA and PMDA/DDS printed via a polysalt vat photopolymerization route are compared by SEM, SAXS/WAXS, and TGA. PDMA/DDS displays reduced π‐stacking and lower thermal stability compared to PMDA/ODA.
Erin C. Jackson   +8 more
wiley   +1 more source

Carboxylato-prism[6]arene as a supramolecular catalyst in water: exploiting its deep hydrophobic cavity for green oxidation of aromatic amines. [PDF]

open access: yesChem Sci
Del Regno R   +8 more
europepmc   +1 more source

Recent Advances in Conductive Rubber Composites: Progress, Challenges, and Emerging Opportunities

open access: yesMacromolecular Rapid Communications, EarlyView.
This study reviews the recent advances in conductive rubber composites, focusing on key aspects such as material selection, conductive mechanisms, interfacial engineering, processing methods, vulcanization strategies, and practical applications. It also discusses current challenges and highlights emerging directions that are shaping the development of ...
Lu Yin   +3 more
wiley   +1 more source

Searching for Novel Antiviral Agents as COVID19 Treatments: Guanidino Diaryl Thioureas. [PDF]

open access: yesChemMedChem
Minneci M   +6 more
europepmc   +1 more source

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

open access: yesChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda   +7 more
wiley   +1 more source

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