Results 51 to 60 of about 71,285 (330)

An Ultrafast Self‐Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine

Advanced Functional Materials, EarlyView.
A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang, Zhangrui Wu, Xiansheng Zhao, Geng Wang, Quyang Yang, Minxia zhang, Xiaowei Wang, Xiujun Cheng, Changyue Wu, Dan Wu, Yutian Yang, Canbin Dong, Tao Zhang, Weiqiang Tan, Ningwen Zhu   +14 more
wiley   +1 more source

1,2,6-thiadiazinones as novel narrow spectrum calcium/calmodulin-dependent protein kinase kinase 2 (CaMKK2) inhibitors [PDF]

, 1983
We demonstrate for the first time that 4H-1,2,6-thiadiazin-4-one (TDZ) can function as a chemotype for the design of ATP-competitive kinase inhibitors. Using insights from a co-crystal structure of a 3,5-bis(arylamino)-4H-1,2,6-thiadiazin-4-one bound to ...
Asquith, Christopher R.M., Godoi, Paulo H., Counago, Rafael M., Laitinen, Tuomo, Scott, John W., Langendorf, Christopher G., Oakhill, Jonathan S., Drewry, David H., Zuercher, William J., Koutentis, Panayiotis A., Willson, Timothy M., Kalogirou, Andreas S.   +11 more
core   +3 more sources

Novel Functional Materials via 3D Printing by Vat Photopolymerization

Advanced Functional Materials, EarlyView.
This Perspective systematically analyzes strategies for incorporating functionalities into 3D‐printed materials via Vat Photopolymerization (VP). It explores the spectrum of achievable functionalities in recently reported novel materials—such as conductive, energy‐storing, biodegradable, stimuli‐responsive, self‐healing, shape‐memory, biomaterials, and
Sergey S. Nechausov, Patrick Fesser, Boris A. Bulgakov, Ulrich S. Schubert   +3 more
wiley   +1 more source

Characteristics of denatured rapeseed oil during storage and refining processes

Grasas y Aceites, 2000
In 1981, toxic oil syndrome, a progressive multi-system disease caused by consumption of rapeseed oil denatured with aniline occurred in Spain. To date, the causal toxic agent or agents remain unknown.
M. V. Ruiz-Méndez, M. Posada de la Paz, B. Blount, H. Schurz Rogers, N. Castro-Molero, R. M. Philen   +5 more
doaj   +1 more source

Synthesis and Cytotoxicity Assay of Aniline Substituted Thienopyrimidines for Anti-Colorectal Cancer Activity

Results in Chemistry, 2023
Colorectal cancer ranks third among all cancers worldwide. Colorectal cancer is treated using a variety of therapies and methods. Almost 1 million deaths are caused every year. The treatment is very ineffective against the cancer cells.
Mahalakshmi Suresha Biradar, Shachindra L. Nargund, Shankar Thapa   +2 more
doaj   +1 more source

In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography [PDF]

, 2008
The biodistribution profiles in mice of two pyrrole-imidazole polyamides were determined by PET. Pyrrole-imidazole polyamides are a class of small molecules that can be programmed to bind a broad repertoire of DNA sequences, disrupt transcription factor ...
Bergstr  m, Burns, Chou, D. A. Harki, D. B. Stout, Dervan, Dervan, Dudouet, Edelson, Gross, Harapanhalli, Hsu, K  hnast, Lee, Lendvai, M. E. Phelps, N. Satyamurthy, P. B. Dervan, Phelps, Phelps, Poethko, Puckett, Roivainen, Schottelius, Tavitian, Toyokuni, Trauger   +26 more
core   +3 more sources

Pioneering the Future: Principles, Advances, and Challenges in Organic Electrodes for Aqueous Ammonium‐Ion Batteries

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
Leveraging the numerous advantages of ammonium‐ion (NH₄⁺)—including cost‐effectiveness, low corrosiveness, preferential orientation, and rapid diffusion kinetics—aqueous NH₄⁺ batteries (AAIBs) have gained significant attention. This review highlights and evaluates the progress of AAIBs utilizing organic electrode materials such as small molecules ...
Mangmang Shi, Xiaoyan Zhang
wiley   +1 more source

Substituted 1,1,1-triaryl-2,2,2-trifluoroethanes and processes for their synthesis [PDF]

, 1988
Synthetic procedures are disclosed for tetraalkyls, tetraacids, and dianhydrides substituted 1,1,1-triaryl 2,2,2-trifluoroethanes which comprises: (1) 1,1-bis (dialkylaryl) 1-aryl 2,2,2-trifluoroethane, (2) 1,1-bis (dicarboxyaryl) 1-aryl 2,2,2 ...
Alston, William B., Gratz, Roy F.
core   +2 more sources

Lead identification and structure-activity relationships of heteroarylpyrazole arylsulfonamides as allosteric CC-chemokine receptor 4 (CCR4) antagonists [PDF]

, 2014
A knowledge-based library of aryl 2,3-dichlorophenylsulfonamides was synthesised and screened as human CCR4 antagonists, in order to identify a suitable hit for the start of a lead-optimisation programme.
Copley, R.C.B., Miah, A.H., O'Flynn, D., Percy, J.M., Procopiou, P.A.   +4 more
core   +1 more source

Unravelling the Atomic Structure of a Metal‐Covalent Organic Framework Assembled from Ruthenium Metalloligands

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
Metal‐covalent organic frameworks (MCOFs) are novel porous materials that exhibit the advantages of covalent and metal‐organic frameworks. However, it is extremely difficult to resolve their atomic structure and better understand their structure‐properties relation. This work utilizes a synergistic combination of advanced microscopy, spectroscopic, and
Seán Hennessey, Roberto González‐Gómez, Nicolás Arisnabarreta, Anna Ciotti, Jing Hou, Nadezda V. Tarakina, Andrey Bezrukov, Kunal S. Mali, Michael Zaworotko, Steven De Feyter, Max García‐Melchor, Pau Farràs   +11 more
wiley   +1 more source