Results 41 to 50 of about 79,431 (246)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Biopsychosocial benefits of animal-assisted activities for children aged 8–16 years from providers' perspectives

open access: yesInternational Journal of Adolescence and Youth
This study aimed to explore the biopsychosocial benefits of animal-assisted activities for children aged 8–16 years from providers' perspectives. Through qualitative interviews and thematic analysis, seven key themes were identified: ‘provision of ...
Trudy Harkness, Anne Moorhead
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Role of Pet-Based Activities: Working with Rabbits to Improve Self-Esteem in Preschool Children

open access: yesAnimals
Animal-assisted activities (AAAs) effectively improve the self-esteem of infants and young children, thereby playing a significant role in their growth into adolescence.
Sang-Hwan Kim
doaj   +1 more source

Animal-assisted interventions: Possibilities and limitations of implementation in young persons with developmental disabilities and behavioral disorders [PDF]

open access: yesSpecijalna Edukacija i Rehabilitacija, 2018
The type of complementary treatment under the interdisciplinary term Animal-assisted interventions - AAI implies all types of interventions which integrate a variety of animals within two key modalities: Animal-Assisted Activities - AAA and Animal ...
Milanović-Dobrota Biljana
doaj  

Dog Welfare, Well-Being and Behavior: Considerations for Selection, Evaluation and Suitability for Animal-Assisted Therapy

open access: yesAnimals, 2020
Health care and human service providers may include dogs in formal intervention settings to positively impact human physical, cognitive and psychosocial domains.
Melissa Winkle   +2 more
doaj   +1 more source

Animal Assisted Therapy and Activities in Alzheimer's Disease [PDF]

open access: yes, 2013
This book section discusses animal assisted therapy and its effect on chronic diseases like Alzheimer's Disease.
Sibel Cevizci   +3 more
openaire   +1 more source

The role of physical activity in animal-assisted interventions for autism: A systematic review

open access: yesNeurodiversity, 2023
Purpose: Animal-assisted interventions (AAIs) may have therapeutic effects for autism. Physical activity (PA) has many established benefits for autism. AAIs appear to involve PA, which may drive some of their beneficial effects. The purpose of this review was to quantify the extent to which AAIs involve PA and to describe the PA dose.
Ann-Marie Sylvia   +2 more
openaire   +1 more source

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