Results 61 to 70 of about 149,644 (286)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Classes de comportamentos constituintes de intervenções de psicólogos no subcampo de atuação profissional de psicoterapia com apoio de cães [PDF]

open access: yes, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Psicologia.O cão foi a primeira espécie animal a ser domesticada. O início dessa interação remonta há aproximadamente 12
Garcia, Murilo Pereira
core  

An Arthroscopy-Assisted Mini-Invasive Technique to Create a Chronic Rabbit Model With Massive and Retracted Supraspinatus Rotator Cuff Tears

open access: yesArthroscopy Techniques, 2022
Understanding the pathophysiology of rotator cuff tears (RCTs) in animal models is of great importance, as it helps in the development of repair strategies and therapeutic treatments for rotator cuff diseases in humans.
Junjie Xu, M.D.   +3 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Cortisol Levels of Shelter Dogs in Animal Assisted Interventions in a Prison: An Exploratory Study

open access: yes, 2021
Previous studies regarding the Animal Assisted Interventions (AAI) have mainly focused on the beneficial effects of human–animal interactions on human health; whereas the impact of such activities on the welfare of the animals involved has received ...
Luigi Sacchettino   +6 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Canicross Pilot Programme: Basic Considerations for Its Implementation as an Extracurricular Sports Activity

open access: yesEducation Sciences
Canicross is a sport that consists of running while being pulled by a dog in a natural environment. Due to the benefits to health and well-being that it brings to the people and dogs that practise it, this sport could be implemented as an animal-assisted
Xabier Gonzalez-Santamaria   +3 more
doaj   +1 more source

The Impact of Physiotherapy in the Water Assisted by Dolphins for Motor Skills of Patient after Haemorrhagic Stroke (Case Analysis)

open access: yesReabilitacijos Mokslai: Slauga, Kineziterapija, Ergoterapija, 2019
Background. Stroke is one of the leading causes of morbidity, mortality and long-term disability worldwide. In terms of innovative technologies which help to recover from stroke one of the newest and least researched methods is physiotherapy in the water
Evelina Rimkutė   +2 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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