Results 91 to 100 of about 223,666 (304)

A Commentary on Perspectives of the Pet Effect: Exploring Public Awareness, Community Impact, and Public Policy Implications

Pets
Today, the pet effect is a powerful symbol for advancing the understanding and acceptance of the human–animal bond in societal and policy arenas. The primary aim of this commentary is to clarify the concept of the “pet effect” and demonstrate how ...
Aubrey H. Fine, Zenithson Ng, Matthew P. Knight, Taylor Chastain Griffin, Lindsey Braun, Steven Feldman   +5 more
doaj   +1 more source

Integrating animals in the classroom: The attitudes and experiences of Australian school teachers toward animal-assisted interventions for children with Autism Spectrum Disorder

Pet Behaviour Science, 2016
The introduction of animals into school classrooms has been posited as a beneficial intervention for individuals with Autism Spectrum Disorder (ASD). Whilst evidence that animal-assisted interventions or activities can positively influence classroom ...
Bradley P Smith, Ashley A Dale
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents [PDF]

, 2017
peer-reviewedThe gut hormone glucagon-like peptide (GLP)-1 and its analogues represent a new generation of anti-diabetic drugs, which have also demonstrated propensity to modulate host lipid metabolism.
Cryan, John F., Dinan, Timothy G., Kent, Robert M., Mandal, Rupasri, Murphy, Kiera, O’Connor, Paula M., Patterson, Elaine, Peterson, Veronica L., Ross, R Paul, Ryan, Paul M, Seeley, Randy J., Stack, Helena, STANTON, CATHERINE, Wishart, David S.   +13 more
core   +5 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The Role of Animal-Assisted Therapy in Enhancing Patients’ Well-Being: Systematic Study of the Qualitative and Quantitative Evidence

JMIRx Med
BackgroundAnimal-assisted therapy, also known as pet therapy, is a therapeutic intervention that involves animals to enhance the well-being of individuals across various populations and settings.
Ramendra Pati Pandey, Himanshu, Gunjan, Riya Mukherjee, Chung-Ming Chang   +4 more
doaj   +1 more source

A within farm clinical trial to compare two treatments (parenteral antibacterials and hoof trimming) for sheep lame with footrot [PDF]

, 2010
From observational studies, farmers who use parenteral antibacterials to promptly treat all sheep with footrot (FR) or interdigital dermatitis (ID) have a prevalence of lameness of
Abecia, Binns, Christley, Depiazzi, E.M. King, Egerton, Everett-Hincks, Fitzpatrick, Forcada, G.J. Wassink, Goddard, Goldstein, Green, Green, Grogono-Thomas, J.C. Brown, Kaler, Kaler, Kaler, Kaler, L.E. Green, L.J. Moore, Marshall, Mellor, MLC, Moore, Nieuwhof, Nieuwhof, O’Doherty, R. Grogono-Thomas, Rasbash, Rhind, Schwartzkoff, Sterk, Stewart, Wassink, Wassink, Williams, Winter   +38 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Donkey-assisted therapy in mental health conditions: a systematic review

Frontiers in Psychiatry
IntroductionThis paper evaluates the effectiveness of donkey-assisted therapy in neurodevelopmental disorders in children, adolescents, and adults.MethodsRegistered in the PROSPERO database (CRD42025644921) and conducted according to Preferred Reporting ...
Alessia Fulgenzi, Antonio Raffa, Carmela De Domenico, Marcella Di Cara, Simona Leonardi, Adriana Piccolo, Fabio Mauro Giambò, Giulia Marafioti, Angelo Alito, Giulia Leonardi, Laura Turriziani, Michele Panzera, Angelo Quartarone, Francesca Cucinotta   +13 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source