Results 41 to 50 of about 50,152 (244)

A Systematic Review of Equine-Assisted Interventions in Military Veterans Diagnosed with PTSD

Journal of Veterans Studies, 2019
Military veterans transitioning from active duty to civilian life often face challenges during the reintegration process. Reintegration can become more difficult when a veteran is coping with posttraumatic stress disorder (PTSD) and its sequelae ...
Lisa Boss, Sandy Branson, Heather Hagan, Cheryl Krause-Parello   +3 more
doaj   +1 more source

The Selection and Training of Shelter Dogs for Involvement in Canine-Assisted Interventions: What Are the Ethical Issues?

Veterinary Sciences
Managing relinquished/stray dogs is a significant socio-economic and ethical challenge necessitating structured policies to ensure animal welfare and integration into society.
Laura Contalbrigo, Elizabeth A. Walsh, Lieve L. Meers, Daniele Benedetti, Marta De Santis, Emma Bassan, Simona Normando   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Scoping Review on Salivary Oxytocin and Vasopressin Measurement in the Dog

Animals
Oxytocin (OT) and vasopressin (AVP) are attracting interest as potential measures for dog welfare and human-dog interactions. The potential for detection and measurement of these two neuropeptides in canine saliva provides a viable alternative to more ...
Marta De Santis, Margherita Soncin, Valentina Bertazzo, Luca Martelli, Diletta Fornasiero, Franco Mutinelli, Laura Contalbrigo   +6 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Recommendations for uniform terminology in animal-assisted services (AAS)

Human-Animal Interactions
Through the years, the range of services involving animals benefiting people, often described as “animal-assisted interventions” (AAIs), has been plagued with confusing and inconsistent taxonomy, terminology, and definitions. This has caused difficulties
Amy Johnson Binder, Nancy Parish-Plass, Meg Kirby, Melissa Winkle, Daniela Plesa Skwerer, Laura Ackerman, Cindy Brosig, Wendy Coombe, Esther Delisle, Marie-Jose Enders-Slegers, Jo-Ann Fowler, Laura Hey, Tiffani Howell, Michael Kaufmann, Mariana Kienast, Miyako Kinoshita, Debbie Ngai, Brigitte Wijnen   +17 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An umbrella review of the evidence for equine‐assisted interventions

Australian Journal of Psychology, 2019
Objective To establish the evidence base for animal‐assisted interventions, and specifically, hippotherapy and other interventions involving horses, in the context of improving biological, physical, psychological and social functioning, and outcomes in ...
Cindy Stern, Anna Chur‐hansen
doaj   +1 more source