Results 51 to 60 of about 3,987,549 (272)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Utilizing animal assisted interventions in elementary schools [PDF]

, 2014
Master's Project (M.Ed.) University of Alaska Fairbanks, 2014Animal Assisted Interventions in the elementary school counseling setting involves the school counselor choosing to bring in an animal, commonly a dog, to assist in counseling interventions ...
France, Catherine E.
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Human-Animal Bonding in Animal-Assisted Interventions in Counseling [PDF]

, 2019
Animal-assisted interventionists incorporating an animal into clinical practice must harness the human–animal bond for therapeutic benefit. Therapists have a duty to understand the complex relational processes occurring in this modality (Stewart, Chang ...
Buechener-Maxwell, Virginia, Robino, Ariann Evans   +1 more
core  

Animal Assisted Interventions: Views of Social Workers from Gävleborg

, 2016
This thesis was conducted in order to explore the views and perception of social workers from Gävleborg on animal-assisted interventions. This study examines the attitudes of social workers towards the phenomenon of animal-assisted interventions and the ...
Eklund, Carin, Melnace, Gita
core   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Recommendations for uniform terminology in animal-assisted services (AAS)

Human-Animal Interactions
Through the years, the range of services involving animals benefiting people, often described as “animal-assisted interventions” (AAIs), has been plagued with confusing and inconsistent taxonomy, terminology, and definitions. This has caused difficulties
Amy Johnson Binder, Nancy Parish-Plass, Meg Kirby, Melissa Winkle, Daniela Plesa Skwerer, Laura Ackerman, Cindy Brosig, Wendy Coombe, Esther Delisle, Marie-Jose Enders-Slegers, Jo-Ann Fowler, Laura Hey, Tiffani Howell, Michael Kaufmann, Mariana Kienast, Miyako Kinoshita, Debbie Ngai, Brigitte Wijnen   +17 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

An umbrella review of the evidence for equine‐assisted interventions

Australian Journal of Psychology, 2019
Objective To establish the evidence base for animal‐assisted interventions, and specifically, hippotherapy and other interventions involving horses, in the context of improving biological, physical, psychological and social functioning, and outcomes in ...
Cindy Stern, Anna Chur‐hansen
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source