Results 71 to 80 of about 50,232 (244)

Describing adverse events in an animal-assisted intervention organization: Recommendations for prevention and management

Human-Animal Interactions
Little is known about adverse events surrounding animal-assisted interventions (AAIs) since they are reluctantly reported and uncommonly discussed in the literature.
Zenithson Ng, Laurence Svensson, Marcy Souza, Julia Albright   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

For the love of acronyms: An analysis of terminology and acronyms used in AAI research 2013–2023

Human-Animal Interactions
The involvement of animals to assist or facilitate activities, education, or therapy has become increasingly popular. As we recognize animals’ roles in ameliorating well-being and educational outcomes, researchers and programmers are developing a variety
Freya L.L. Green, Mikaela L. Dahlman, Arielle Lomness, John-Tyler Binfet   +3 more
doaj   +1 more source

Elephant in the room: animal assisted interventions [PDF]

BMJ, 2019
Ratschen, Elena, Sheldon, Trevor Andrew
openaire   +4 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Animal-Assisted Interventions: A Literature Review on Diverse Applications of Animal-Assisted Interventions in selected medical entities in different age groups

Journal of Education, Health and Sport
This literature review examines the therapeutic role of Animal-Assisted Interventions (AAIs) in promoting physical and mental well-being for diverse populations.
Agnieszka Najdek, Dorota Szewczyk, Julia Nowak, Aleksandra Woźniak, Michał Jakub Cioch, Marcin Mycyk, Urszula Kaczmarska, Daria Oleksy, Katarzyna Doman, Kamil Hermanowicz, Dawid Komada   +10 more
doaj   +1 more source

Animal-assisted interventions as innovative tools for mental health

Annali dell'Istituto Superiore di Sanità, 2011
There is a growing interest for the potential health benefits of human-animal interactions. Although scientific evidence on the effects is far from being consistent, companion animals are used with a large number of human subjects, ranging from children ...
Francesca Cirulli, Marta Borgi, Alessandra Berry, Nadia Francia, Enrico Alleva   +4 more
doaj   +1 more source