Results 81 to 90 of about 4,857,250 (280)
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Animal welfare in dog-assisted services: Perception of professionals in Germany
Using a questionnaire and open questions, with the data compiled in SPSS and MS Excel, this study analyzes the perception, significance, and understanding of animal welfare in dogs in animal-assisted services from the perspective of animal-assisted ...
Katharina Ameli +2 more
doaj +1 more source
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Integrative Animal-Assisted Therapy
Animal-assisted therapy has been shown to present a number of benefits, yet it is newer to the mental health field. This research study explored interest and knowledge regarding animal-assisted therapy from the perspective of professionals providing care
Janna M. Marschall
core
Animal-Assisted Therapy: Motives and Rewards [PDF]
Animal-assisted therapy is a complimentary therapy utilized in health care to provide goal-directed therapy using dogs. The purpose of this study was to understand what motivates individuals to being animal-assisted volunteering and rewards that ...
Collins, Kailee Victoria
core +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Beyond the Five Freedoms: Welfare Concerns of Farm-Based Therapy and Education
Suzanne M. Kapral, Risë VanFleet
doaj +1 more source
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source

