Results 101 to 110 of about 146,853 (284)
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
An explorative study of the perceptions of social workers who are exposed to work-related, secondary traumatic experiences through their clientele, of the psychosocial support Equine Assisted Therapy (E.A.T) could provide [PDF]
, 2013 Includes abstract.Includes bibliographical references.This study emanates from the fact that trauma is an increasing reality in our society and it has a particular focus on social workers who work with clientele that have been exposed to and who have ...
Garland, Sarah
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Animal-assisted therapy in health-care facilities [PDF]
How does the use of animal-assisted therapy compared to the lack of animal-assisted therapy affect the psychological well being of all ...
Milazzo, Haley +2 more
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FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Human animal interaction, animal assisted therapy and pet ownership in neurorehabilitation
Advances in Clinical Neuroscience & Rehabilitation, 2020 Edwards, Laura
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Who\u27s Helping Who:The Benefits of Animal-Assisted Therapy [PDF]
, 2015 Animal-Assisted Therapy (AAT) is a supportive goal-oriented intervention that is based on human and animal interaction. There are different types of Animal-Assisted Therapy, some of these are equine, canine, feline, and others.
Hunter, Jamie
core