Results 121 to 130 of about 146,853 (284)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Analyzing intervention research trends in animal-assisted therapy: a review on the Korean experimental researches from 1998 to 2022. [PDF]

J Anim Sci Technol, 2023
Kil T.
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

USE OF ANIMAL ASSISTED THERAPY/ACTIVITIES IN SOCIAL FIELD [PDF]

, 2012
In my thesis I occupy with using of animal assisted therapy/activities in social field, its methods and application. The aim was to describe the kinds of animal therapy, describe various ways and methods of using animals in therapy, explain the basic ...
HOŠKOVÁ, Jitka
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Australian University Students’ Experience of Animal-Assisted Education: An Exploratory Study

Animals
University students experience poorer mental health outcomes when compared to the general population. Poor mental health has been associated with reduced wellbeing and low academic performance, resulting in higher rates of withdrawal.
Jessica Hill, Lucy Waldby, Teresa Quinlan, Jennifer Fleming, Melanie Hoyle, Carlie Driscoll   +5 more
doaj   +1 more source

Role of pets and animal assisted therapy in suicide prevention. [PDF]

Ann Med Surg (Lond), 2022
Shoib S, Hussaini SS, Chandradasa M, Saeed F, Khan T, Swed S, Lengvenyte A.   +6 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Bridging The Gap Between Occupational Therapy & Animal-Assisted Therapy (AAT) [PDF]

The Doctoral Capstone Project involves developing advocacy resources to support occupational therapy practitioners in the ethical, safe, and effective integration of animal-assisted therapy (AAT) into clinical practice.
Campbell Smith, Aspen
core