Results 111 to 120 of about 146,853 (284)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Studi Meta-Analisis : Efektifitas Animal-Assisted Therapy untuk Menurunkan Kecemasan

Jurnal Penelitian Pendidikan, Psikologi dan Kesehatan
Penelitian ini merupakan studi meta analisis yang bertujuan untuk meninjau efektifitas intervensi animal-assisted therapy dalam menurunkan kecemasan. Penelitian melibatkan 13 jurnal yang telah disortir menggunakan metode PRISMA. Analisis dilakukan dengan
Redualita Christy Kumowal, Ananta Yudiarso   +1 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

A Text-Mining Analysis of Research Trends in Animal-Assisted Therapy. [PDF]

Animals (Basel), 2023
Lee SJ, Kim GH, Moon YH, Lee SS.
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Equine therapy in the management of teenagers with anorexia nervosa: a qualitative study

Eating and Weight Disorders
Background Anorexia nervosa is a complex psychiatric pathology with limited therapeutic tools to reduce morbidity and mortality. Equine-assisted therapy could provide additional therapeutic benefits.
Camille Lepy, Aurélie Letranchant, Jean-Luc Aniorte, Julien Bedos, Rebecca Hotchkin, Maurice Corcos, Marion Robin, Marie-Aude Piot   +7 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Donkey-assisted therapy in mental health conditions: a systematic review

Frontiers in Psychiatry
IntroductionThis paper evaluates the effectiveness of donkey-assisted therapy in neurodevelopmental disorders in children, adolescents, and adults.MethodsRegistered in the PROSPERO database (CRD42025644921) and conducted according to Preferred Reporting ...
Alessia Fulgenzi, Antonio Raffa, Carmela De Domenico, Marcella Di Cara, Simona Leonardi, Adriana Piccolo, Fabio Mauro Giambò, Giulia Marafioti, Angelo Alito, Giulia Leonardi, Laura Turriziani, Michele Panzera, Angelo Quartarone, Francesca Cucinotta   +13 more
doaj   +1 more source

Animal-assisted therapy in eating disorder treatment: A systematic review. [PDF]

Eat Behav, 2022
Fennig MW, Weber E, Santos B, Fitzsimmons-Craft EE, Wilfley DE.   +4 more
europepmc   +1 more source