Results 111 to 120 of about 169 (169)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Animals and Words: Talking about Animals – Talking with Animals – Talking Animals

, 2014
openaire   +2 more sources

To Animate or Not to Animate, that is the Question [PDF]

Proceedings of the Human Factors and Ergonomics Society Annual Meeting, 1997
Animation presented together with voice narration in a computer presented tutorial did not facilitate learning when compared with a text and static graphics tutorial. The tutorials were the same except for the addition of simple animations and voice narration.
Chris M. Herdman, Richard F. Dillon, Jo Wood, Tracy D. Hutcheson   +3 more
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Animal animation

Philosophia, 2001
The original publication can be found at www.springerlink.com ; Andrew ...
openaire   +3 more sources

Animation/Re-animation

Theory, Culture & Society, 2006
10.1177/026327640602300261 ; Theory, Culture and Society ; 23 ; 2-3 ...
openaire   +2 more sources

When is an animal, not an animal?

Journal of Biological Education, 1981
The concepts of ‘animal’ held by some New Zealand primary, secondary, and tertiary students were explored using both an interview and multiplechoice survey approach. The results indicate that many students of all ages have a restricted concept of ‘animal’ compared with that of a biologist. The implications of these results for teaching are discussed.
openaire   +2 more sources

Animal Research (See Animal Ethics; Animal Welfare; Animal Cloning)

2021
The use of animals in scientific research appears to be almost as old as the beginning of medicine. For example, vivisection is already reported in the Corpus Hippocraticum (4th to 1st century BC) and by Galen (2nd century). The use of animals was strongly revived in the Renaissance.
Maria do Céu Patrão Neves, Henk ten Have   +1 more
openaire   +2 more sources