Results 111 to 120 of about 10,141,254 (408)

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Expression of Interleukin-8 Promotes Neutrophil Infiltration and Genetic Instability in Mutatect Tumors

open access: yesNeoplasia: An International Journal for Oncology Research, 2000
Neutrophils represent a potential source of genotoxic reactive oxygen and nitrogen species in the tumor microenvironment. Using Mutatect cell lines, which can form subcutaneous tumors in syngeneic C57BL/6 mice, we have previously established that the ...
Arsalan S. Haqqani   +2 more
doaj   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

open access: yesFEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää   +2 more
wiley   +1 more source

The Case for In Vitro Meat

open access: yesVoices in Bioethics, 2016
Long gone are the days of hunting and gathering food or raising our own livestock.  The first time American consumers see their food is usually on a supermarket shelf or a restaurant plate. It’s easy to not consider what goes into the preparation of milk,
James Ninia
doaj   +1 more source

Animal welfare in the reformed Common Agricultural Policy: wherefore art thou? [PDF]

open access: yes, 2015
Against the backdrop of the recently reformed Common Agricultural Policy (CAP), this article considers the potential for improved standards of farm animal welfare within the Treaty objectives of the European Union.
Ryland, Diane
core   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

La conscience d’Argo. Svevo au pays des chiens qui parlent

open access: yesItalies, 2006
Dans un texte bref, sans doute tardif et peut-être inachevé, Argo e il suo padrone, Svevo a voulu présenter au lecteur les mémoires d’un chien doué de parole, retranscrits en italien par son maître.
Denis Ferraris
doaj   +1 more source

Factors associated with student grades in Animal Physiology I [PDF]

open access: yes, 2004
Students and faculty alike would like to know what factors are related to success in college courses. The purpose of this study was to evaluate factors that relate to a student’s success in Animal Physiology I (Phys I), an upper-level animal science ...
Hale, Margo, Rosenkrans, Charles
core   +2 more sources

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

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