We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová+14 more
wiley +1 more source
Environmental and biological drivers of movement activity in Callimico goeldii under zoo conditions. [PDF]
Nieckarz Z+3 more
europepmc +1 more source
Palaeontology or A systematic summary of extinct animals and their geological relations
Richard Owen
openalex +2 more sources
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy+9 more
wiley +1 more source
The association between total, animal-based, and plant-based protein intake and cognitive decline in older adults. [PDF]
Peperkamp M+3 more
europepmc +1 more source
IV. Observations on the structure of the different cavities, which constitute the stomach of the whale, compared with those of ruminating animals, with a view to ascertain the situation of the digestive organ [PDF]
Everard Home
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster+3 more
wiley +1 more source
Rifles and shotguns have similar animal welfare outcomes during aerial culling of non-native fallow deer (<i>Dama dama</i>). [PDF]
Forsyth DM+5 more
europepmc +1 more source