Results 1 to 10 of about 5,412,710 (314)
BMC Veterinary Research, 2019 Background Porcine circovirus type 3 (PCV3) is an emerging circovirus species, that has been reported in major pig-raising countries including the United States, China, South Korea, Brazil, Spain, and Poland.
Huanan Wang +13 more
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Scientific Reports, 2021 Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer in the clinic. Further discovery of novel drugs or therapeutic protocols that enhance efficacy requires reliable animal models that recapitulate human immune responses to ICI
Ikumi Katano +9 more
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Frontiers in Immunology, 2023 IntroductionPorcine reproductive and respiratory syndrome virus (PRRSV) remains one of the most threatening pathogens of swine. The nucleocapsid (N) protein is the major structural protein of the virus and has been used as a PRRSV diagnostic antigen due ...
Yuening Cheng +6 more
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Isolation and characterization of Bordetella pseudohinzii in mice in China
Animal Models and Experimental Medicine, 2019 We report on the first detection and isolation of B. pseudohinzii (Bordetella pseudohinzii) in laboratory mice in China. Forty‐one B. pseudohinzii strains were isolated from 3094 mice in 33 different laboratory animal facilities in southern China.
Lei Ma +8 more
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Prediction of Compound Synthesis Accessibility Based on Reaction Knowledge Graph
Molecules, 2022 With the increasing application of deep-learning-based generative models for de novo molecule design, the quantitative estimation of molecular synthetic accessibility (SA) has become a crucial factor for prioritizing the structures generated from ...
Baiqing Li, Hongming Chen
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Biology Open, 2016 Tumor necrosis factor alpha (TNFα) plays a key role in the pathogenesis of rheumatoid arthritis (RA). Blockade of TNFα by monoclonal antibody has been widely used for the therapy of RA since the 1990s; however, its mechanism of efficacy, and potential ...
Ge Li +6 more
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Laboratory animal anaesthesia [PDF]
Canadian Anaesthetists’ Society Journal, 1973 On a decrit des methodes en ce qui concerne l'anesthesic locale et generale chez les animaux experiment aux.
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Veterinary Medicine International, 2015 This study was to establish a systemic C. parapsilosis infection model in immunosuppressed ICR mice induced by cyclophosphamide and evaluate the antifungal efficiency of fluconazole. Three experiments were set to confirm the optimal infectious dose of C.
Yu’e Wu +7 more
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Frontiers in Microbiology, 2018 More and more dogs have been used as a disease model for medical research and drug safety evaluation. Therefore, it is important to make sure that the dogs and their living houses are special pathogen free.
Miaoli Wu +7 more
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Allergy to laboratory animals in laboratory technicians and animal keepers. [PDF]
Occupational and Environmental Medicine, 1986 The prevalence of allergy to laboratory animals (LAA) was investigated in laboratory technicians and animal keepers. In a questionnaire 41 of 101 technicians reported symptoms provoked by work with laboratory animals. On clinical investigation 30 were found to have symptoms and signs related to contact with animals, and allergy was confirmed by ...
G, Agrup +3 more
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