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Chemoprevention in experimental animals [PDF]
Annals of the New York Academy of Sciences, 2011 The potential cancer‐preventive effects of resveratrol, evident from the data obtained by various studies, are summarized in this review. Resveratrol (trans‐3,5,4′‐trihydroxystilbene), a naturally occurring polyphenolic compound, was first isolated in 1940 as a constituent of the roots of white Hellebore (Veratrum grandiflorumO. Loes), and is now found
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Laboratory animal: biological reagent or living being?
Brazilian Journal of Medical and Biological Research, 2014 The duties of humans toward non-human animals and their rights in society have been debated for a long time. However, a discussion on the terminology used for the identification of laboratory animals is usually not considered, although the employment of ...
C.V.P. Cardoso, A.E.C.C. de Almeida
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Confronting the bias towards animal experimentation (animal methods bias)
Frontiers in Drug DiscoveryLaws and policies are in place around the world to promote the replacement and reduction of nonhuman animals in science. These principles are rooted not just in ethical considerations for animals, but also in scientific considerations regarding the ...
Catharine E. Krebs +2 more
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Animals in Moral Limbo: How Literary Pigs May Help Lab-Generated Ones
Animals, 2020 When considering that artistic and literary artifacts reflect the cultural views and mores of a particular time period, there is a significant misalignment between stories depicting increased moral status of pigs (e.g., vis-à-vis human-porcine ...
Nancy Tuck
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Frontiers in Cellular and Infection MicrobiologyIntroductionMethicillin-resistant Staphylococcus aureus (MRSA) infections have become arduous to treat due to their capacity to form biofilms, develop persistence, and exhibit significant antimicrobial resistance.
Priyanka +11 more
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Asbestosis in Experimental Animals [PDF]
Occupational and Environmental Medicine, 1963 Previous animal experiments with asbestos dusts have been almost entirely confined to chrysotile asbestos. It was, therefore, decided to investigate the effects of mill dusts from the three types of asbestos that are produced commercially in South Africa, namely chrysotile, amosite, and crocidolite.
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Humane Endpoints in Swiss Webster Mice Infected with Toxoplasma gondii RH Strain
AnimalsThe highly virulent Toxoplasma gondii RH strain is maintained through successive passages in mice, but there is still a lack of studies that refine these procedures from a 3Rs perspective, where humanitarian ideals aim to minimize the stress, pain, or ...
Igor Falco Arruda +7 more
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Canadian Journal of Bioethics, 2022 Despite the international 3Rs principles that recommends replacing, reducing and refining the use of animals in medical experimentation, it remains difficult to obtain funding in Canada for medical research that respects these principles, particularly ...
William-Philippe Girard +2 more
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Results of experimental modeling of postoperative peritoneal adhesions
Patologìâ, 2019 Objective: Optimization of postoperative intraabdominal adhesions modeling. Material and methods. The objects of the study were 17 mature rats of the Wistar line of both sexes weighing 200–250 g.
M. H. Melnychenko +2 more
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Smart Materials in MedicineDue to the increasing commercial activities and adventure travels, millions of people visit high-altitude regions every year. A rapid increase in altitude results in high-altitude cerebral edema (HACE), an acute form of HAI characterized by altered ...
Yaqin Chen +8 more
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