Results 31 to 40 of about 1,691,707 (91)

“It’s Not Good for the Animals, but I Think It Should Be Done”—Using Focus Group Interviews to Explore Adolescent Views on Animal Experimentation

open access: yesAnimals, 2022
The present study focused on an in-depth analysis of adolescents’ (aged 15–16) attitudes towards animal experimentation. Focus group interviews were conducted to gain a deeper understanding regarding the ethical considerations of this age group. The data
Sonja M. Enzinger, Christian Dürnberger
doaj   +1 more source

Establishment of Novel Genotoxicity Assay System Using Murine Normal Epithelial Tissue-Derived Organoids

open access: yesFrontiers in Genetics, 2021
Short-/middle-term and simple prediction studies for carcinogenesis are needed for the safety assessment of chemical substances. To establish a novel genotoxicity assay with an in vivo mimicking system, we prepared murine colonic/pulmonary organoids from
Masami Komiya   +8 more
doaj   +1 more source

Evaluation of the macroscopic growth degree of experimental endometriosis in rats Avaliação do grau de crescimento macroscópico da endometriose experimental em ratos

open access: yesActa Cirúrgica Brasileira, 2007
PURPOSE: To evaluate macroscopically the growth degree of self-transplantation of endometriosis in rats. METHODS: Forty female rats, after a 7-day period for adpating and evaluating of the estrous cycle regularity, underwent tail abdominal midline ...
João Nogueira Neto   +5 more
doaj   +1 more source

Historical Issues Concerning Animal Experimentation in the United States

open access: yes, 1981
The use of animals for research and teaching has now become an issue of great concern in the United States. In contrast to the legislative systems in Britain, Scandinavia and many European countries, American scientists can pursue research projects with ...
Sechzer, Jeri A.
core   +1 more source

Confronting the bias towards animal experimentation (animal methods bias)

open access: yesFrontiers in Drug Discovery
Laws and policies are in place around the world to promote the replacement and reduction of nonhuman animals in science. These principles are rooted not just in ethical considerations for animals, but also in scientific considerations regarding the ...
Catharine E. Krebs   +2 more
doaj   +1 more source

Laboratory animal: biological reagent or living being?

open access: yesBrazilian Journal of Medical and Biological Research, 2014
The duties of humans toward non-human animals and their rights in society have been debated for a long time. However, a discussion on the terminology used for the identification of laboratory animals is usually not considered, although the employment of ...
C.V.P. Cardoso, A.E.C.C. de Almeida
doaj   +1 more source

Animals in Moral Limbo: How Literary Pigs May Help Lab-Generated Ones

open access: yesAnimals, 2020
When considering that artistic and literary artifacts reflect the cultural views and mores of a particular time period, there is a significant misalignment between stories depicting increased moral status of pigs (e.g., vis-à-vis human-porcine ...
Nancy Tuck
doaj   +1 more source

Comprehensive safety and toxicity analysis of 2,2’-Bipyridine derivatives in combating MRSA biofilm formation and persistence

open access: yesFrontiers in Cellular and Infection Microbiology
IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) infections have become arduous to treat due to their capacity to form biofilms, develop persistence, and exhibit significant antimicrobial resistance.
Priyanka   +11 more
doaj   +1 more source

Animal Experimentation

open access: yes, 2019
Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans.

core   +1 more source

Humane Endpoints in Swiss Webster Mice Infected with Toxoplasma gondii RH Strain

open access: yesAnimals
The highly virulent Toxoplasma gondii RH strain is maintained through successive passages in mice, but there is still a lack of studies that refine these procedures from a 3Rs perspective, where humanitarian ideals aim to minimize the stress, pain, or ...
Igor Falco Arruda   +7 more
doaj   +1 more source

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