Results 51 to 60 of about 163,394 (292)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

UNIVERSITY OF MELBOURNE ANIMAL EXPERIMENTATION ETHICS COMMITTEE MINUTES [PDF]

, 1992
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/71250The
University of Melbourne. Animal Experimentation Ethics Committee
core  

Animals in Moral Limbo: How Literary Pigs May Help Lab-Generated Ones

Animals, 2020
When considering that artistic and literary artifacts reflect the cultural views and mores of a particular time period, there is a significant misalignment between stories depicting increased moral status of pigs (e.g., vis-à-vis human-porcine ...
Nancy Tuck
doaj   +1 more source

Asbestosis in Experimental Animals [PDF]

Occupational and Environmental Medicine, 1963
Previous animal experiments with asbestos dusts have been almost entirely confined to chrysotile asbestos. It was, therefore, decided to investigate the effects of mill dusts from the three types of asbestos that are produced commercially in South Africa, namely chrysotile, amosite, and crocidolite.
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

FOR OUR CHILDREN: THE ETHICS OF ANIMAL EXPERIMENTATION IN THE AGE OF GENETIC ENGINEERING [PDF]

, 2010
Preface -- 1. Introduction: animal experimentation, public opinion, and philosophical debate -- 2. Five ethical prototypes of animal experimentation -- 3. The case for "weak human priority" -- 4.
Nordgren, Anders
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Guideline Checklist for Publishing Research Papers on Animal Experimentation and Comparative Medicine in China (2024 Edition) [PDF]

The standardization, transparency, and completeness of research papers in animal experimentation and comparative medicine research are crucial for ensuring the credibility, reproducibility, and clinical applicability of research findings. Internationally
Editorial Board of Laboratory Animal and Comparative Medicine
core   +1 more source

Humane Endpoints in Swiss Webster Mice Infected with Toxoplasma gondii RH Strain

Animals
The highly virulent Toxoplasma gondii RH strain is maintained through successive passages in mice, but there is still a lack of studies that refine these procedures from a 3Rs perspective, where humanitarian ideals aim to minimize the stress, pain, or ...
Igor Falco Arruda, Maria Regina Reis Amendoeira, Thamires Francisco Bonifácio, Clarissa Nascimento da Silveira Raso, Hyago da Silva Medeiros Elidio, Jhônata Willy Rocha Coelho, Luiz Cesar Cavalcanti Pereira da Silva, Isabele Barbieri dos Santos   +7 more
doaj   +1 more source

ANIMAL EXPERIMENTATION AND TUBERCULOSIS

Journal of the American Medical Association, 1910
ETIOLOGY Everything that we know to-day of the etiology of tuberculosis, everything that has a direct bearing on the prevention and control of the disease, we owe to animal experimentation. Before the infectious nature of the tubercle became established by animal experimentation no advance was made in the knowledge of tuberculosis in any direction ...
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source