Results 71 to 80 of about 162,718 (292)

Animal experimentation

open access: yes, 2007
Why consider opposing viewpoints? -- Introduction -- Ch. 1: Do animals have rights? -- Chapter preface -- 1. Animals have rights / Tom Regan -- 2. Animals do not have rights / Ilana Mercer -- 3.
Henig, Robin, M.
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

MINUTE BOOKS OF THE ANIMAL EXPERIMENTATION COMMITTEE / ANIMAL EXPERIMENTATION ETHICS COMMITTEE

open access: yes, 1991
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/71226The
University of Melbourne. Animal Experimentation Ethics Committee
core  

Animal experimentation and scientific knowledge: a thought style?

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2010
Animal experimentation, besides a research method extensively applied in the production of scientific knowledge, is also considered essential to science and with undeniable historical relevance in advances in human health. In this survey, a questionnaire
Thales de Astrogildo e Tréz
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

UNIVERSITY OFMELBOURNE ANIMAL EXPERIMENTATION ETHICS COMMITTEE WORKING PARTY ON ANIMAL FACILITES

open access: yes, 1991
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
University of Melbourne. Animal Experimentation Ethics Committee
core  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

UNIVERSITY OF MELBOURNE ANIMAL EXPERIMENTATION ETHICS COMMITTEE MINUTES

open access: yes, 1992
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/71250The
University of Melbourne. Animal Experimentation Ethics Committee
core  

The 1, 2, 3 of laboratory animal experimentation

open access: yesRevista Peruana de Medicina Experimental y Salud Pública, 2016
The slow scientific development in Latin America in recent decades has delayed the incorporation of laboratory animal experimentation; however, this situation has started to change.
Wilber Romero-Fernandez   +7 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

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