Results 71 to 80 of about 1,927,178 (242)
UNIVERSITY OF MELBOURNE ANIMAL EXPERIMENTATION ETHICS COMMITTEE MINUTES
, 1992 This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/71250The
University of Melbourne. Animal Experimentation Ethics Committee
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Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
FOR OUR CHILDREN: THE ETHICS OF ANIMAL EXPERIMENTATION IN THE AGE OF GENETIC ENGINEERING
, 2010 Preface -- 1. Introduction: animal experimentation, public opinion, and philosophical debate -- 2. Five ethical prototypes of animal experimentation -- 3. The case for "weak human priority" -- 4.
Nordgren, Anders
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Animal Experimentation: Lessons From Human Experimentation
, 2007 This article is adapted from the author\u27s presentation during the panel discussion Animals in Research: Pet Cloning, Patents, and Bioethics at the 14th Annual Animal Law Conference of Lewis & Clark Law School on October 14, 2006.
LaFrance, Arthur Birmingham
core +1 more source
Animal experimentation and scientific knowledge: a thought style?
Brazilian Journal of Pharmaceutical Sciences, 2010 Animal experimentation, besides a research method extensively applied in the production of scientific knowledge, is also considered essential to science and with undeniable historical relevance in advances in human health. In this survey, a questionnaire
Thales de Astrogildo e Tréz
doaj +1 more source
Speculative Philosophy, the Troubled Middle, and the Ethics of Animal Experimentation
, 1989 Even to begin discussing the ethics of animal experimentation we must locate our place in the "ethical three-ring circus" of the debate among "human welfarists," "animal rightists" and those in the "troubled middle." A philosophy of "nature alive ...
Donnelley, Strachan
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Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source