Results 61 to 70 of about 163,394 (292)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Animal Experimentation Needs Dissection [PDF]
, 1998 lette
O'Sullivan, Helen +3 more
core +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Smart Materials in MedicineDue to the increasing commercial activities and adventure travels, millions of people visit high-altitude regions every year. A rapid increase in altitude results in high-altitude cerebral edema (HACE), an acute form of HAI characterized by altered ...
Yaqin Chen +8 more
doaj +1 more source
Results of experimental modeling of postoperative peritoneal adhesions
Patologìâ, 2019 Objective: Optimization of postoperative intraabdominal adhesions modeling. Material and methods. The objects of the study were 17 mature rats of the Wistar line of both sexes weighing 200–250 g.
M. H. Melnychenko +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 1984 This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/62615The
University of Melbourne. Animal Experimentation Committee
core
Animal Experimentation and Animal Welfare: Lessons from the European Union
Journal of Animal Law, Ethics and One HealthThis article examines the regulatory framework governing the use of animals in scientific research in the European Union (EU) and analyses the extent to which this can limit animal use and promote animal welfare.
Leila Mohaghegh, Masoud Shamaei
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Secondary victims of animal experimentation: psychosocial hazards in animal laboratories
JME Practical BioethicsThis essay makes the case that laboratory animal personnel are at risk of becoming secondary victims as a consequence of their work in animal experimentation.
David Shaw +5 more
doaj +1 more source