Results 41 to 50 of about 5,619,627 (312)

Isolation and characterization of Bordetella pseudohinzii in mice in China

open access: yesAnimal Models and Experimental Medicine, 2019
We report on the first detection and isolation of B. pseudohinzii (Bordetella pseudohinzii) in laboratory mice in China. Forty‐one B. pseudohinzii strains were isolated from 3094 mice in 33 different laboratory animal facilities in southern China.
Lei Ma   +8 more
doaj   +1 more source

Prediction of Compound Synthesis Accessibility Based on Reaction Knowledge Graph

open access: yesMolecules, 2022
With the increasing application of deep-learning-based generative models for de novo molecule design, the quantitative estimation of molecular synthetic accessibility (SA) has become a crucial factor for prioritizing the structures generated from ...
Baiqing Li, Hongming Chen
doaj   +1 more source

'Human-on-a-chip' developments: A translational cuttingedge alternative to systemic safety assessment and efficiency evaluation of substances in laboratory animals and man?

open access: yes, 2022
S.235-257Various factors, including the phylogenetic distance between laboratory animals and humans, the discrepancy between current in vitro systems and the human body, and the restrictions of in silico modelling, have generated the need for new ...
Lindner, G.   +9 more
core   +1 more source

Establishment and evaluation of a transgenic mouse model of arthritis induced by overexpressing human tumor necrosis factor alpha

open access: yesBiology Open, 2016
Tumor necrosis factor alpha (TNFα) plays a key role in the pathogenesis of rheumatoid arthritis (RA). Blockade of TNFα by monoclonal antibody has been widely used for the therapy of RA since the 1990s; however, its mechanism of efficacy, and potential ...
Ge Li   +6 more
doaj   +1 more source

Laboratory animal anaesthesia [PDF]

open access: yesCanadian Anaesthetists’ Society Journal, 1973
On a decrit des methodes en ce qui concerne l'anesthesic locale et generale chez les animaux experiment aux.
openaire   +2 more sources

Systemic Candida parapsilosis Infection Model in Immunosuppressed ICR Mice and Assessing the Antifungal Efficiency of Fluconazole

open access: yesVeterinary Medicine International, 2015
This study was to establish a systemic C. parapsilosis infection model in immunosuppressed ICR mice induced by cyclophosphamide and evaluate the antifungal efficiency of fluconazole. Three experiments were set to confirm the optimal infectious dose of C.
Yu’e Wu   +7 more
doaj   +1 more source

Alternatives to Carbon Dioxide—Taking Responsibility for Humanely Ending the Life of Animals

open access: yesAnimals, 2019
Carbon dioxide (CO2) is commonly used to kill rodents. However, a large body of research has now established that CO2 is aversive to them. A multidisciplinary symposium organized by the Swiss Federal Food Safety and Veterinary Office discussed the ...
Shannon Axiak Flammer   +8 more
doaj   +1 more source

Allergy to laboratory animals in laboratory technicians and animal keepers. [PDF]

open access: yesOccupational and Environmental Medicine, 1986
The prevalence of allergy to laboratory animals (LAA) was investigated in laboratory technicians and animal keepers. In a questionnaire 41 of 101 technicians reported symptoms provoked by work with laboratory animals. On clinical investigation 30 were found to have symptoms and signs related to contact with animals, and allergy was confirmed by ...
G, Agrup   +3 more
openaire   +2 more sources

LISTROPHORID MITES ON LABORATORY ANIMALS IN PUERTO RICO [PDF]

open access: yes, 1979
LISTROPHORID MITES ON LABORATORY ANIMALS IN PUERTO RICOLISTROPHORID MITES ON LABORATORY ANIMALS IN PUERTO ...
Fox, Irving
core   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh   +4 more
wiley   +1 more source

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