Results 41 to 50 of about 7,438,473 (359)

Development of a sensitive and specific xMAP assay for detection of antibodies against infectious laryngotracheitis and bronchitis viruses

open access: yesVirology Journal, 2018
Background A serological method to simultaneously detect antibodies against infectious laryngotracheitis virus (ILTV) and infectious bronchitis virus (IBV) is imperative for the differential diagnosis and evaluation of antibodies titers after vaccination.
Huanan Wang   +8 more
doaj   +1 more source

Innovations and advances in modelling and measuring pain in animals

open access: yesNature Reviews Neuroscience, 2021
Best practices in preclinical algesiometry (pain behaviour testing) have shifted over the past decade as a result of technological advancements, the continued dearth of translational progress and the emphasis that funding institutions and journals have ...
K. Sadler, J. Mogil, C. Stucky
semanticscholar   +1 more source

Laboratory animal allergy

open access: yesJournal of Allergy and Clinical Immunology, 1998
Approximately one third of laboratory animal workers have occupational allergy to animal danders, and a third of these have symptomatic asthma. Sensitization generally occurs with the first 3 years of employment, and risk factors include atopic background, as well as job description as it relates to the intensity of exposure.
R K, Bush, R A, Wood, P A, Eggleston
openaire   +2 more sources

Enrichment for Laboratory Zebrafish—A Review of the Evidence and the Challenges

open access: yesAnimals, 2021
Simple Summary The zebrafish is one of the most commonly used animals in scientific research, but there remains a lack of consensus over good practice for zebrafish housing and care.
Chloe Stevens   +2 more
semanticscholar   +1 more source

Development of a real-time loop-mediated isothermal amplification assay for detection of porcine circovirus 3

open access: yesBMC Veterinary Research, 2019
Background Porcine circovirus type 3 (PCV3) is an emerging circovirus species, that has been reported in major pig-raising countries including the United States, China, South Korea, Brazil, Spain, and Poland.
Huanan Wang   +13 more
doaj   +1 more source

Development of a novel humanized mouse model for improved evaluation of in vivo anti-cancer effects of anti-PD-1 antibody

open access: yesScientific Reports, 2021
Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer in the clinic. Further discovery of novel drugs or therapeutic protocols that enhance efficacy requires reliable animal models that recapitulate human immune responses to ICI
Ikumi Katano   +9 more
doaj   +1 more source

Identificationof a novel linear epitope on the porcine reproductive and respiratory syndrome virus nucleocapsid protein, as recognized by a specific monoclonal antibody

open access: yesFrontiers in Immunology, 2023
IntroductionPorcine reproductive and respiratory syndrome virus (PRRSV) remains one of the most threatening pathogens of swine. The nucleocapsid (N) protein is the major structural protein of the virus and has been used as a PRRSV diagnostic antigen due ...
Yuening Cheng   +6 more
doaj   +1 more source

Does the Stress of Laboratory Life and Experimentation on Animals Adversely Affect Research Data? A Critical Review

open access: yesAlternatives to laboratory animals : ATLA, 2018
Recurrent acute and/or chronic stress can affect all vertebrate species, and can have serious consequences. It is increasingly and widely appreciated that laboratory animals experience significant and repeated stress, which is unavoidable and is caused ...
Jarrod Bailey
semanticscholar   +1 more source

Isolation and characterization of Bordetella pseudohinzii in mice in China

open access: yesAnimal Models and Experimental Medicine, 2019
We report on the first detection and isolation of B. pseudohinzii (Bordetella pseudohinzii) in laboratory mice in China. Forty‐one B. pseudohinzii strains were isolated from 3094 mice in 33 different laboratory animal facilities in southern China.
Lei Ma   +8 more
doaj   +1 more source

Prediction of Compound Synthesis Accessibility Based on Reaction Knowledge Graph

open access: yesMolecules, 2022
With the increasing application of deep-learning-based generative models for de novo molecule design, the quantitative estimation of molecular synthetic accessibility (SA) has become a crucial factor for prioritizing the structures generated from ...
Baiqing Li, Hongming Chen
doaj   +1 more source

Home - About - Disclaimer - Privacy