Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source
Effectiveness of electrical stunning and bleeding in finishing pigs: a case study from procedures to practice at two modern Colombian abattoirs. [PDF]
Pastrana-Camacho AP+3 more
europepmc +1 more source
Contributions of the Amygdala to Emotion Processing: From Animal Models to Human Behavior
E. Phelps, Joseph E LeDoux
semanticscholar +1 more source
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh+5 more
wiley +1 more source
Correction to Investigation on Anti-Diarrheal and Antipyretic Activities of <i>Citrus maxima</i> Seeds in Swiss Albino Mice Model. [PDF]
europepmc +2 more sources
Animal-chlorophyte photosymbioses: evolutionary origins and ecological diversity. [PDF]
Liao IJ+5 more
europepmc +1 more source
On the Preparations of the Indian Hemp, or gunjah: Cannabis Indica Their Effects on the Animal System in Health, and their Utility in the Treatment of Tetanus and other Convulsive Diseases [PDF]
W. B. O'Shaughnessy
openalex +1 more source
Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza+5 more
wiley +1 more source
The use of a severity index to analyse impact of bacterial zoonoses on welfare of wildlife populations. [PDF]
Hirst K, Halsey S.
europepmc +1 more source