Results 71 to 80 of about 10,395,939 (358)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

A new direction for farm animal genetic resources [PDF]

open access: yes, 2009
In September 2007, the International Technical Conference on Animal Genetic Resources for Food and Agriculture was held in Interlaken, Switzerland. Two important documents aiming at preventing the genetic erosion of farm animal biodiversity and promoting
Kantanen, Juha
core  

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

The Animal That Therefore I Am

open access: yesIn the Tree Where the Double Sex Sleeps, 2019
The Animal That Therefore I Am is the long-awaited translation of the complete text of Jacques Derrida's ten-hour address to the 1997 Cerisy conference entitled "The Autobiographical Animal," the third of four such colloquia on his work.
J. Derrida
semanticscholar   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Estimation of Economic Direct Losses due to Livestock Brucellosis in Iran (2003-2014)

open access: yesمجله اپیدمیولوژی ایران, 2017
Background and Objectives: Brucellosis in livestock has led to a significant reduction in the economic capital in Iran. Estimation of the economic losses due to this disease helps to highlight the importance of the disease and makes it easy to justify ...
Z Boluki   +6 more
doaj  

Development of an advisory system that supports good animal welfare in organic production in Norway [PDF]

open access: yes, 2004
Organic agriculture wishes to emphasise animal welfare, and aims to be at the forefront with regard to promoting the welfare of farm animals. It is therefore important to increase the expertise in the field of animal welfare in organic farming systems ...
Henriksen, Britt I. F.
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Quantifying the errors in animal contacts recorded by proximity loggers [PDF]

open access: hybrid, 2021
Federico Ossi   +8 more
openalex   +1 more source

Animal suicide: An account worth giving? Commentary on Peña-Guzmán on Animal Suicide [PDF]

open access: yes, 2018
Peña-Guzmán (2017) argues that empirical evidence and evolutionary theory compel us to treat the phenomenon of suicide as continuous in the animal kingdom.
Mikhalevich, Irina
core  

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