Results 121 to 130 of about 6,732,583 (287)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Healthcare professionals’ attitudes to animal assisted activity with dogs in paediatric care

open access: yesComplementary Therapies in Clinical Practice
Hospitalization for children often involves stress induced by fear and pain. Complementary therapies, such as Animal Assisted Activities (AAA) with dogs, can alleviate the hospital experience.The first aim of this study was to initiate the development of an instrument that measures healthcare professionals' attitudes toward complementary therapy ...
M. Lindstrom Nilsson   +4 more
openaire   +3 more sources

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Animal-assisted social work at Flash Farm

open access: yes
INTRODUCTION: Flash Farm (FF) is a purpose-built therapeutic farm where people come to undertake animal-assisted social work (SW) including animal assisted educational activities to improve social, emotional, and cognitive wellbeing.
Natasha Long (11369346)   +3 more
core  

For Pet’s Sake: Being the animal advocate in animal-assisted interactions [PDF]

open access: yes, 2013
The main goal in the applications of animal-assisted interventions has largely been geared toward benefiting and ensuring the safety of the human. While this will always remain the principal concern, it must be balanced with advocating for the safety and
Ng, Zenithson Y
core  

Evaluating Stress in Dogs Involved in Animal-Assisted Interventions

open access: yes, 2019
Animal-assisted interventions (AAIs) are co-therapies in which the animal is an integral and active part of the treatment process. Dogs are widely involved in AAI projects, but little data are available to determine if AAI sessions are a source of stress
Miriam Ferrara   +2 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Human-Animal Bonding in Animal-Assisted Interventions in Counseling [PDF]

open access: yes, 2019
Animal-assisted interventionists incorporating an animal into clinical practice must harness the human–animal bond for therapeutic benefit. Therapists have a duty to understand the complex relational processes occurring in this modality (Stewart, Chang ...
Buechener-Maxwell, Virginia   +1 more
core  

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