Results 131 to 140 of about 6,732,583 (287)

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Opportunities, challenges, and practical considerations in implementing animal-assisted activities in primary school classrooms [PDF]

Animal-Assisted Activities (AAA) are increasingly used in education to improve learning and support students’ social and emotional development. This study explores primary schools teachers experiences of doing/using animal-assisted activities with dogs ...
Engelbrecht, Marjana
core  

Animal-Assisted Psychoeducational Intervention in Paediatric Oncohaematology: Evidence from a Single-Centre Observational Study

Children
Background: Hospitalisation for paediatric oncohaematological diseases entails significant physical and psychological stress, often compromising children’s emotional regulation and daily functioning.
Chiara Battaglini, Valentina Isaja, Gaia Riscossa, Mario Giordano, Paola Quarello, Giulia Zucchetti, Franca Fagioli   +6 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Animal-assisted support programs for residents in Canadian long-term care homes: a feasibility and acceptability study

BMC Geriatrics
Background Animal-assisted services, specifically animal-assisted support programs (AASPs, pet therapy, animal-assisted therapy, animal-assisted activities), are promising programs that may improve the mental health and overall well-being of older adults
Brittany S. DeGraves, Hannah M. O’Rourke, Colleen Dell, Heather Titley, Carole A. Estabrooks   +4 more
doaj   +1 more source

“He's opening everybody's heart up”: Co-creating pet therapy activities with inpatients at a large urban mental health and addictions hospital

Social Sciences and Humanities Open
Background: Animal-Assisted Activities (AAA) is now ubiquitous in many health care settings around the world. There is growing evidence about AAA's benefits but there is no literature about the inclusion of patients, the end-user, in the design and ...
Laura Sikstrom, Chelcie Soroka, Csilla Kalocsai, Theresa Conforti, Eva Katz, Sophie Soklaridis   +5 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Animal-Assisted Activities for Students with Disabilities: Obtaining Stakeholders’ Approval and Planning Strategies for Teachers

, 2014
Animal-human interactions have been found to have positive influences on children across the world. In particular, research supports the benefits of animal-assisted activities in addressing students\u27 social and behavioral problems within the classroom
Cho, Jeong il, Baumgartner, E
core  

Effects of static and dynamic canine-assisted intervention in young adults: sex differences in hormonal, EEG, HRV, and emotional responses

Scientific Reports
As mental health disorders like depression and anxiety rise, animal-assisted intervention (AAI) has emerged as a promising complementary approach, recognized for its psychological benefits.
Yujin Song, Youngwook Jung, Kayoung Yang, Kyongwon Yoo, Youngtae Heo, Minjung Yoon   +5 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source