Results 41 to 50 of about 4,857,461 (280)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Use of “Non-Traditional” Animal-Assisted Interventions in Children: A Scoping Review

European Journal of Investigation in Health, Psychology and Education
Animal-assisted interventions (AAI) are increasingly used to support pediatric health, education, and psychosocial well-being. While most research has focused on dogs and horses, a growing body of literature has examined the use of other less traditional
Margaret E. Gruen, Navika Mittal, Peggy Gross, Mariam A. Hamad, Anika R. Kadumpalli, Rebecca J. Harney, David C. Dorman   +6 more
doaj   +1 more source

Therapeutic Role of Animals: A Comprehensive Literature Review on the Prevalent Forms and Species in Animal-Assisted Interventions

Journal of Education, Health and Sport, 2023
Animals have been valued and used to improve human physical and mental health since ancient times. Animal-assisted therapy (AAT) is a complementary approach to traditional medicine, involving trained animals.
Dorota Szewczyk, Jakub Fiega, Milena Michalska, Urszula Żurek, Zuzanna Lubaszka, Ewa Sikorska   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Animal-Assisted Therapy In Elementary Schools [PDF]

, 2014
Animal-assisted therapy (AAT) is becoming increasingly popular in school and therapeutic settings across the country (Friesen, 2010). In animal-assisted therapy (AAT), a certified therapy animal works in partnership with the counselor and/or the dog ...
Kurschner, Steve
core  

Impact of Covid-19 on Animal Assisted Therapy in Pediatric Oncology: A Child Life Specialist Perspective

, 2023
An ongoing comprehensive review of child life specialists’ perspective in the United States implies that Covid-19 negatively impacted animal assisted therapy (AAT) usage in all eligible children’s hospitals.
Williams, Savanna M, NC DOCKS at East Carolina University   +1 more
core  

Personality and emotional stability in dogs assessed for animal-assisted services: Exploratory findings from APWA-ICofA

Human-Animal Interactions
Background: Dogs working in animal-assisted services (AAS) must be emotionally stable, socially appropriate, and able to cope with diverse and potentially demanding environments.
Christine Olsen, Adam Johnson, Amy Johnson Binder, Melissa Winkle   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Costs, benefits and mechanisms of animal-assisted therapy: adopting a change in perspective

Scottish Journal of Residential Child Care, 2018
Animal-assisted therapy has progressed in recent years, helping a broad spectrum of people to tackle stress, loneliness and health problems, including those with life-long disabilities.
Vanessa A. D. Wilson
doaj   +1 more source